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Toluca vs. Santos Laguna prediction, odds, Liga MX picks [1/14/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Toluca vs Santos Laguna predictions for Liga MX Wednesday.
Liga MX action continues on Wednesday at 10:10 PM ET as Santos Laguna takes on Toluca in the playoffs at .
Based on updated simulations, Dimers' advanced Liga MX model predicts Toluca as the most likely winner of the Toluca vs. Santos Laguna game.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Toluca vs. Santos Laguna prediction: Who will win?
Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's Liga MX matchup between Toluca and Santos Laguna 10,000 times as part of our Liga MX predictions coverage.
Our independent predictive model currently indicates an 81.9% chance of Toluca winning, a 6.6% chance for Santos Laguna, and an 11.5% chance of a draw.
Toluca vs. Santos Laguna odds
We have sourced the best Liga MX odds in America for this game, which are listed here:
| Market | Toluca | Santos Laguna | Draw |
|---|---|---|---|
| Moneyline | -500 | +1200 | +700 |
All odds are correct at the time of publication and are subject to change.
Toluca vs. Santos Laguna picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Santos Laguna | +1200 |
According to our Liga MX best bets, the top play to make on this game is Santos Laguna to win.
Toluca vs. Santos Laguna: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 3-0 Toluca win being the most probable:
| Final Score | Probability |
|---|---|
| TOL 3-0 SLA | 10.2% |
| TOL 2-0 SLA | 10.1% |
| TOL 5-0 SLA | 8.7% |
When it comes to the both teams to score (BTTS) market, we project a 51.8% chance that both Toluca and Santos Laguna score, and a 48.2% probability of at least one team keeping a clean sheet.
These predictions are based on each team's average score after 10,000 simulations.
Toluca vs. Santos Laguna game-day updates and essential details
Wednesday's action between Toluca and Santos Laguna is scheduled to start at 10:10 PM ET.
- Who: Toluca vs. Santos Laguna
- Date: Wednesday, January 14, 2026
- Time: 10:10 PM ET/7:10PM PT
Conclusion
According to our computer model, Toluca has an 81.9% win probability on Wednesday, Santos Laguna has a 6.6% win probability, and there is an 11.5% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Toluca vs. Santos Laguna insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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