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Guadalajara vs. Cruz Azul prediction, odds, Liga MX picks [5/16/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Guadalajara vs Cruz Azul predictions for Liga MX Saturday.
Guadalajara and Cruz Azul will meet in the Liga MX playoffs on Saturday, starting at 9:07 PM ET.
Based on updated simulations, Dimers' advanced Liga MX model projects that a draw is the most likely result of the Guadalajara vs. Cruz Azul game.
This article offers a closer look at Saturday's match, including best bets and picks.
Guadalajara vs. Cruz Azul prediction: Who will win?
Using powerful machine learning and statistical analysis, we have simulated the result of Saturday's Liga MX game between Guadalajara and Cruz Azul, forming part of our Liga MX predictions coverage.
Our leading predictive model currently suggests a 41.0% chance of Guadalajara winning, a 32.7% chance for Cruz Azul, and a 0.0% chance of a draw.
Guadalajara vs. Cruz Azul odds
We have sourced the best Liga MX odds in America for this game, which are listed here:
- Moneyline: Guadalajara , Cruz Azul
All odds are correct at the time of publication and are subject to change.
Guadalajara vs. Cruz Azul picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Cruz Azul |
According to our Liga MX best bets, the top play to make on this game is **.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Guadalajara vs. Cruz Azul game-day updates and essential details
Saturday's matchup between Guadalajara and Cruz Azul is scheduled to begin at 9:07 PM ET.
- Who: Guadalajara vs. Cruz Azul
- Date: Saturday, May 16, 2026
- Time: 9:07 PM ET/6:07PM PT
Conclusion
According to our computer model, Guadalajara has a 41.0% win probability on Saturday, Cruz Azul has a 32.7% win probability, and there is a 0.0% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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