Cruz Azul vs. Pumas UNAM prediction, odds, Liga MX picks [5/21/2026]

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Written by Ryan Leaver

Get Cruz Azul vs Pumas UNAM predictions for Liga MX Thursday.

Cruz Azul-Pumas UNAM Predictions and Game Preview.
Cruz Azul vs. Pumas UNAM Liga MX prediction for Thursday, May 21, 2026.

Liga MX action continues on Thursday at 10:00 PM ET as Pumas UNAM takes on Cruz Azul in the playoffs at .

Based on updated simulation results, Dimers' advanced Liga MX model predicts Cruz Azul as the most likely winner of the Cruz Azul vs. Pumas UNAM game.

This article offers an expanded analysis of Thursday's match, including best bets and picks.

Cruz Azul vs. Pumas UNAM prediction: Who will win?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Thursday's Liga MX matchup between Cruz Azul and Pumas UNAM, forming part of our Liga MX predictions coverage.

Our leading predictive model currently suggests a 55.3% chance of Cruz Azul winning, a 21.5% chance for Pumas UNAM, and a 23.3% chance of a draw.

 

Cruz Azul vs. Pumas UNAM odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Market Cruz Azul Pumas UNAM Draw
Moneyline -140 +320 +295

All odds are correct at the time of publication and are subject to change.

Cruz Azul vs. Pumas UNAM picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Pumas UNAM +320

According to our Liga MX best bets, the top play to make on this game is Pumas UNAM to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Cruz Azul vs. Pumas UNAM: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

Final Score Probability
CAZ 1-1 PUM 11%
CAZ 1-0 PUM 10.8%
CAZ 2-1 PUM 9.8%

When it comes to the both teams to score (BTTS) market, we project a 53.1% chance of both sides finding the net and a 46.9% chance that at least one doesn’t.

These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score may differ from our predicted winner.

Cruz Azul vs. Pumas UNAM game-day updates and essential details

Thursday's action between Cruz Azul and Pumas UNAM is scheduled to begin at 10:00 PM ET.

  • Who: Cruz Azul vs. Pumas UNAM
  • Date: Thursday, May 21, 2026
  • Time: 10:00 PM ET/7:00PM PT

Conclusion

According to our computer model, Cruz Azul has a 55.3% win probability on Thursday, Pumas UNAM has a 21.5% win probability, and there is a 23.3% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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