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Guadalajara vs. Puebla prediction, odds, Liga MX picks [4/18/2026]

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Written by Ryan Leaver

Get Guadalajara vs Puebla predictions for Liga MX Saturday.

Guadalajara-Puebla Predictions and Game Preview.
Guadalajara vs. Puebla Liga MX prediction for Saturday, April 18, 2026.

Liga MX action continues on Saturday at 9:07 PM ET as Puebla takes on the favored Guadalajara in the playoffs at Estadio Akron.

Based on updated simulation results, Dimers' proven Liga MX model projects Guadalajara as the most likely winner of the Guadalajara vs. Puebla game.

This article offers further insights into Saturday's match, including best bets and picks.

Guadalajara vs. Puebla prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Saturday's Liga MX matchup between Guadalajara and Puebla, forming part of our Liga MX predictions coverage.

Our independent predictive model currently suggests a 68.5% chance of Guadalajara winning, a 12.8% chance for Puebla, and an 18.7% chance of a draw.

 

Guadalajara vs. Puebla odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Market Guadalajara Puebla Draw
Moneyline -340 +800 +450

All odds are correct at the time of publication and are subject to change.

Guadalajara vs. Puebla picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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