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Guadalajara vs. Club Leon prediction, odds, Liga MX picks [3/18/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Guadalajara vs Club Leon predictions for Liga MX Wednesday.
Liga MX action continues on Wednesday at 10:07 PM ET as Club Leon takes on the favored Guadalajara in the playoffs at Estadio Akron.
Based on updated simulation results, Dimers' advanced Liga MX model projects Guadalajara as the most likely winner of the Guadalajara vs. Club Leon game.
This article offers further insights into Wednesday's matchup, including best bets and picks.
Guadalajara vs. Club Leon prediction: Who will win?
Using trusted machine learning and statistical analysis, we have simulated the result of Wednesday's Liga MX game between Guadalajara and Club Leon 10,000 times as part of our Liga MX predictions coverage.
Our leading predictive model currently suggests a 56.9% chance of Guadalajara winning, a 20.0% chance for Club Leon, and a 23.0% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 52% chance of going over, according to our model.
Guadalajara vs. Club Leon odds
We have researched the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Guadalajara | Club Leon | Draw |
|---|---|---|
| -225 | +600 | +380 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -172 | +134 |
All odds are correct at the time of publication and are subject to change.
Guadalajara vs. Club Leon picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Club Leon | +600 |
| Total Goals | Under 2.5 | +134 |
According to our best Liga MX bets, the top play to make on this game is Club Leon to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Guadalajara vs. Club Leon: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 1-0 Guadalajara win being the most probable:
| Final Score | Probability |
|---|---|
| GUA 1-0 LEO | 11.3% |
| GUA 1-1 LEO | 10.9% |
| GUA 2-0 LEO | 10.2% |
When it comes to the both teams to score (BTTS) market, we project a 51.7% chance of both sides finding the net and a 48.3% chance that at least one doesn’t.
Guadalajara vs. Club Leon game-day updates and essential details
Wednesday's game between Guadalajara and Club Leon at Estadio Akron is scheduled to begin at 10:07 PM ET.
- Who: Guadalajara vs. Club Leon
- Date: Wednesday, March 18, 2026
- Time: 10:07 PM ET/7:07PM PT
- Venue: Estadio Akron
Conclusion
According to our computer model, Guadalajara has a 56.9% win probability on Wednesday, Club Leon has a 20.0% win probability, and there is a 23.0% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Guadalajara vs. Club Leon insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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