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Tigres UANL vs. Cruz Azul prediction, odds, Liga MX Semi-Final picks [12/6/2025]

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Written by Ryan Leaver

Get Tigres UANL vs Cruz Azul predictions for Liga MX Saturday.

Tigres UANL-Cruz Azul Predictions and Game Preview.
Tigres UANL vs. Cruz Azul Liga MX prediction for Saturday, December 6, 2025.

Tigres UANL and Cruz Azul will lock horns in the Liga MX playoffs on Saturday, starting at 10:10PM ET.

Based on the latest simulation results, Dimers' advanced Liga MX model predicts Tigres UANL as the most likely winner of the Tigres UANL vs. Cruz Azul game.

This article offers further insights into Saturday's matchup, including best bets and picks.

Tigres UANL vs. Cruz Azul prediction: Who will win?

Using powerful machine learning and data analysis, we have simulated the outcome of Saturday's Liga MX game between Tigres UANL and Cruz Azul 10,000 times as part of our Liga MX predictions coverage.

Our leading predictive model indicates a 49.6% chance of Tigres UANL winning, a 25.8% chance for Cruz Azul, and a 24.6% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 52% chance of going over, according to our model.

 

Tigres UANL vs. Cruz Azul odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Moneyline

Tigres UANL Cruz Azul Draw
-105 +300 +260

Total Goals

Over 2.5 Under 2.5
-140 +110

All odds are correct at the time of publication and are subject to change.

Tigres UANL vs. Cruz Azul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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