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Santos Laguna vs. Queretaro prediction, odds, Liga MX picks [10/26/2025]
Get Santos Laguna vs Queretaro predictions for Liga MX Sunday.

Santos Laguna will take on Queretaro in Liga MX action at Estadio Corona on Sunday, beginning at 7:00PM ET.
Based on updated simulation results, Dimers' advanced Liga MX model predicts Santos Laguna as the most likely winner of the Santos Laguna vs. Queretaro game.
This article offers further insights into Sunday's matchup, including best bets and picks.
Santos Laguna vs. Queretaro prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Sunday's Liga MX matchup between Santos Laguna and Queretaro 10,000 times as part of our Liga MX predictions coverage.
Our independent predictive model suggests a 42.5% chance of Santos Laguna winning, a 31.5% chance for Queretaro, and a 26.0% chance of a draw.
Additionally, the 2.5-goal over/under has a 51% chance of staying under, according to our model.
Santos Laguna vs. Queretaro odds
We have researched the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Santos Laguna | Queretaro | Draw |
|---|---|---|
| +110 | +240 | +250 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -128 | +104 |
All odds are correct at the time of publication and are subject to change.
Santos Laguna vs. Queretaro picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Queretaro | +240 |
| Total Goals | Under 2.5 | +104 |
According to our Liga MX best bets, the top play to make on this game is Queretaro moneyline.
Santos Laguna vs. Queretaro: Correct score and BTTS predictions
Here are the top three most likely final scoresaccording to our model, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| SLA 1-1 QUE | 12.4% |
| SLA 1-0 QUE | 10.3% |
| SLA 2-1 QUE | 8.9% |
When it comes to the both teams to score (BTTS) market, we project a 53.2% chance of the yes hitting, and a 46.8% probability of at least one team keeping a clean sheet.
These predictions are based on each team's average score after 10,000 simulations, meaning the most likely correct score can differ from our predicted winner.
Santos Laguna vs. Queretaro game-day updates and essential details
Sunday's matchup between Santos Laguna and Queretaro at Estadio Corona is scheduled to begin at 7:00PM ET.
- Who: Santos Laguna vs. Queretaro
- Date: Sunday, October 26, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Estadio Corona
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Conclusion
According to our computer model, Santos Laguna has a 42.5% win probability on Sunday, Queretaro has a 31.5% win probability, and there is a 26.0% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Santos Laguna vs. Queretaro insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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