Santos Laguna vs. Club Leon prediction, odds, Liga MX picks [10/18/2025]

Liga MX action continues on Saturday at 7:00PM ET as Club Leon squares off with Santos Laguna at Estadio Corona.

Based on the latest simulation results, Dimers' advanced Liga MX model projects Club Leon as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Santos Laguna vs. Club Leon predictions page.

Santos Laguna vs. Club Leon prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Saturday's Liga MX matchup between Santos Laguna and Club Leon 10,000 times as part of our Liga MX predictions coverage.

Our independent predictive model indicates a 28.0% chance of Santos Laguna winning, a 48.0% chance for Club Leon, and a 24.0% chance of a draw.

Santos Laguna vs. Club Leon odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Market	Santos Laguna	Club Leon	Draw
Moneyline	+170	+150	+260

All odds are correct at the time of publication and are subject to change.

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Santos Laguna vs. Club Leon picks and best bets

Our model's biggest edge in today's Santos Laguna vs. Club Leon matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Santos Laguna vs. Club Leon: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

Final Score	Probability
SLA 1-1 LEO	11.2%
SLA 1-2 LEO	9.5%
SLA 0-1 LEO	9%

When it comes to the both teams to score (BTTS) market, we project a 57.9% chance that both Santos Laguna and Club Leon score, and a 42.1% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score can differ from our predicted winner.

Santos Laguna vs. Club Leon game-day updates and essential details

Saturday's action between Santos Laguna and Club Leon at Estadio Corona is scheduled to start at 7:00PM ET.

• Who: Santos Laguna vs. Club Leon
• Date: Saturday, October 18, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Estadio Corona

Dimers' full preview of Saturday's Santos Laguna vs. Club Leon matchup includes our prediction, picks and the latest betting odds.

Before making any Club Leon vs. Santos Laguna picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, Santos Laguna has a 28.0% win probability on Saturday, Club Leon has a 48.0% win probability, and there is a 24.0% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Santos Laguna vs. Club Leon insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on Liga MX

Keep up with the latest Liga MX news and parlay picks throughout the season.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.