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San Luis vs. Guadalajara prediction, odds, Liga MX picks [1/31/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get San Luis vs Guadalajara predictions for Liga MX Saturday.
Atletico San Luis will face Guadalajara in the Liga MX playoffs at Estadio Alfonso Lastras on Saturday, starting at 6:00 PM ET.
Based on the latest simulation results, Dimers' advanced Liga MX model predicts Guadalajara as the most likely winner of the Atletico San Luis vs. Guadalajara game.
This article offers a closer look at Saturday's matchup, including best bets and picks.
Atletico San Luis vs. Guadalajara prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Saturday's Liga MX game between Atletico San Luis and Guadalajara 10,000 times as part of our Liga MX predictions coverage.
Our independent predictive model indicates a 28.2% chance of Atletico San Luis winning, a 46.4% chance for Guadalajara, and a 25.4% chance of a draw.
Additionally, the over/under total of 2.5 goals also has an equal 50-50 chance of hitting, according to our model.
Atletico San Luis vs. Guadalajara odds
We have researched the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Atletico San Luis | Guadalajara | Draw |
|---|---|---|
| +380 | -135 | +275 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -112 | -108 |
All odds are correct at the time of publication and are subject to change.
Atletico San Luis vs. Guadalajara picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | San Luis | +380 |
| Total Goals | Under 2.5 | -108 |
According to our best Liga MX bets, the top play to make on this game is San Luis to win.
Atletico San Luis vs. Guadalajara: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| ASL 1-1 GUA | 12.1% |
| ASL 0-1 GUA | 10.6% |
| ASL 1-2 GUA | 9.3% |
When it comes to the both teams to score (BTTS) market, we project a 53.2% chance that both Atletico San Luis and Guadalajara score, and a 46.8% probability of at least one team being held goalless.
These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score can differ from our predicted winner.
San Luis vs. Guadalajara game-day updates and essential details
Saturday's action between Atletico San Luis and Guadalajara at Estadio Alfonso Lastras is scheduled to start at 6:00 PM ET.
- Who: Atletico San Luis vs. Guadalajara
- Date: Saturday, January 31, 2026
- Time: 6:00 PM ET/3:00PM PT
- Venue: Estadio Alfonso Lastras
Conclusion
According to our computer model, Atletico San Luis has a 28.2% win probability on Saturday, Guadalajara has a 46.4% win probability, and there is a 25.4% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Atletico San Luis vs. Guadalajara insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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