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Queretaro vs. Santos Laguna prediction, odds, Liga MX picks [2/27/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Queretaro vs Santos Laguna predictions for Liga MX Friday.
Queretaro will face Santos Laguna in the Liga MX playoffs at Estadio La Corregidora on Friday, commencing at 8:00 PM ET.
Based on the latest simulation results, Dimers' proven Liga MX model predicts Queretaro as the most likely winner of the Queretaro vs. Santos Laguna game.
This article offers a closer look at Friday's matchup, including best bets and picks.
Queretaro vs. Santos Laguna prediction: Who will win?
Using innovative machine learning and data, we have simulated the outcome of Friday's Liga MX matchup between Queretaro and Santos Laguna 10,000 times as part of our Liga MX predictions coverage.
Our famous predictive model suggests a 51.1% chance of Queretaro winning, a 24.2% chance for Santos Laguna, and a 24.7% chance of a draw.
Additionally, the over/under total of 2.5 goals also has an equal 50-50 chance of hitting, according to our model.
Queretaro vs. Santos Laguna odds
We have sourced the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Queretaro | Santos Laguna | Draw |
|---|---|---|
| -105 | +270 | +260 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -125 | -110 |
All odds are correct at the time of publication and are subject to change.
Queretaro vs. Santos Laguna picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Queretaro | -105 |
| Total Goals | Under 2.5 | -110 |
According to our Liga MX best bets, the top play to make on this game is Queretaro to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Queretaro vs. Santos Laguna: Correct score and BTTS predictions
Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| QUE 1-1 SLA | 11.7% |
| QUE 1-0 SLA | 11.2% |
| QUE 2-1 SLA | 9.6% |
When it comes to the both teams to score (BTTS) market, we project a 52.1% chance of the yes hitting, and a 47.9% probability of at least one team being held goalless.
These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score may differ from our predicted winner.
Queretaro vs. Santos Laguna game-day updates and essential details
Friday's action between Queretaro and Santos Laguna at Estadio La Corregidora is scheduled to start at 8:00 PM ET.
- Who: Queretaro vs. Santos Laguna
- Date: Friday, February 27, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Estadio La Corregidora
Conclusion
According to our computer model, Queretaro has a 51.1% win probability on Friday, Santos Laguna has a 24.2% win probability, and there is a 24.7% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Queretaro vs. Santos Laguna insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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