Queretaro vs. Guadalajara prediction, odds, Liga MX picks [10/22/2025]

Queretaro will take on Guadalajara in Liga MX action at Estadio La Corregidora on Wednesday, starting at 9:00PM ET.

Based on the latest simulations, Dimers' proven Liga MX model predicts Guadalajara as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Queretaro-Guadalajara game 10,000 times," said Dave Garofolo from Dimers.

"Taking into account the most current updates and numerous additional factors, our prediction gives Queretaro a 22.8% chance of winning, Guadalajara a 50.8% chance, and a 26.3% chance of a draw."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Queretaro vs. Guadalajara predictions page.

Queretaro vs. Guadalajara prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's Liga MX game between Queretaro and Guadalajara 10,000 times as part of our Liga MX predictions coverage.

Our famous predictive model currently suggests a 22.8% chance of Queretaro winning, a 50.8% chance for Guadalajara, and a 26.3% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 58% chance of staying under, according to our model.

Queretaro vs. Guadalajara odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Moneyline

Queretaro	Guadalajara	Draw
+430	-145	+280

Total Goals

Over 2.5	Under 2.5
-112	-108

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Queretaro vs. Guadalajara picks and best bets

Our model's biggest edge in today's Queretaro vs. Guadalajara matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Queretaro vs. Guadalajara: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-0 Guadalajara win being the most probable:

Final Score	Probability
QUE 0-1 GUA	13.7%
QUE 1-1 GUA	12.3%
QUE 0-2 GUA	10.2%

When it comes to the both teams to score (BTTS) market, we project a 45.7% chance of the yes hitting, and a 54.3% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations.

Queretaro vs. Guadalajara game-day updates and essential details

Wednesday's game between Queretaro and Guadalajara at Estadio La Corregidora is scheduled to begin at 9:00PM ET.

• Who: Queretaro vs. Guadalajara
• Date: Wednesday, October 22, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Estadio La Corregidora

Dimers' comprehensive preview of Wednesday's Queretaro vs. Guadalajara matchup includes our prediction, picks and the latest betting odds.

Before making any Guadalajara vs. Queretaro picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Queretaro has a 22.8% win probability on Wednesday, Guadalajara has a 50.8% win probability, and there is a 26.3% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Queretaro vs. Guadalajara insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on Liga MX

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