Atlas vs. Club Leon prediction, odds, Liga MX picks [10/22/2025]

Atlas and Club Leon will lock horns in Liga MX at Estadio Jalisco on Wednesday, starting at 11:00PM ET.

Based on the latest simulations, Dimers' proven Liga MX model predicts Club Leon as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Atlas-Club Leon game 10,000 times," said Dave Garofolo from Dimers.

"Taking into account the most current updates and numerous additional factors, our prediction gives Atlas a 35.8% chance of winning, Club Leon a 39.0% chance, and a 25.2% chance of a draw."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Atlas vs. Club Leon predictions page.

Atlas vs. Club Leon prediction: Who will win?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's Liga MX matchup between Atlas and Club Leon 10,000 times as part of our Liga MX predictions coverage.

Our leading predictive model suggests a 35.8% chance of Atlas winning, a 39.0% chance for Club Leon, and a 25.2% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 53% chance of going over, according to our model.

Atlas vs. Club Leon odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Atlas	Club Leon	Draw
+145	+180	+260

Total Goals

Over 2.5	Under 2.5
-140	+100

All odds are correct at the time of publication and are subject to change.

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Atlas vs. Club Leon picks and best bets

Our model's strongest edge in today's Atlas vs. Club Leon matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Atlas vs. Club Leon: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

Final Score	Probability
ATS 1-1 LEO	11.8%
ATS 1-2 LEO	8.6%
ATS 0-1 LEO	8.6%

When it comes to the both teams to score (BTTS) market, we project a 57.1% chance that both Atlas and Club Leon score, and a 42.9% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score can differ from our predicted winner.

Atlas vs. Club Leon game-day updates and essential details

Wednesday's game between Atlas and Club Leon at Estadio Jalisco is scheduled to commence at 11:00PM ET.

• Who: Atlas vs. Club Leon
• Date: Wednesday, October 22, 2025
• Time: 11:00PM ET/8:00PM PT
• Venue: Estadio Jalisco

Dimers' full preview of Wednesday's Atlas vs. Club Leon matchup includes our prediction, picks and the latest betting odds.

Before making any Club Leon vs. Atlas picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Atlas has a 35.8% win probability on Wednesday, Club Leon has a 39.0% win probability, and there is a 25.2% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Atlas vs. Club Leon insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on Liga MX

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