MLS betting tips: Wednesday's picks include Chicago vs. Miami play [7/22/2026]

Today’s MLS betting tips for July 22, 2026 are here, with Chicago vs. Miami and Montreal vs. Nashville among the top plays identified by our model across Wednesday’s MLS play.

Dimers’ predictive analytics engine runs 24/7, going over the latest soccer odds to find genuine betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of MLS betting tips tonight [7/22, updated 5:08AM ET]

Below, you’ll find today’s top 10 soccer bets, ranked by edge for Wednesday, July 22, 2026.

Miami ML (+115)

• Edge: 10.8%
• Probability: 57.3%
• Matchup: Chicago vs. Miami (7:30PM ET)

Our model has identified value on Miami to defeat Chicago at +115 odds. A 57.3% probability produces an edge of 10.8%, making this the strongest play for today's MLS slate.

Nashville ML (-190)

• Edge: 5.9%
• Probability: 71.4%
• Matchup: Montreal vs. Nashville (8:30PM ET)

Nashville ML carries a 5.9% edge and a probability of 71.4% at -190 odds, according to our model.

Colorado ML (+110)

• Edge: 4.5%
• Probability: 52.1%
• Matchup: San Diego FC vs. Colorado (9:30PM ET)

Colorado ML at +110 odds shows a 4.5% edge, supported by a 52.1% probability in simulations.

Cincinnati ML (+300)

• Edge: 3.7%
• Probability: 28.7%
• Matchup: Vancouver vs. Cincinnati (7:30PM ET)

A 3.7% edge and 28.7% probability makes Cincinnati at the moneyline a value play in the Vancouver vs. Cincinnati matchup, per our model.

Seattle vs. Austin Under 2.5 goals (+125)

• Edge: 3.3%
• Probability: 47.7%
• Matchup: Seattle vs. Austin (9:30PM ET)

Seattle vs. Austin Under 2.5 goals at +125 odds presents a 3.3% edge, with simulations resulting in a probability of 47.7%.

San Jose ML (-179)

• Edge: 3.1%
• Probability: 67.2%
• Matchup: Orlando vs. San Jose (10:30PM ET)

Our model finds value on San Jose to win at -179 odds, supported by an edge of 3.1%.

Portland ML (+143)

• Edge: 2.9%
• Probability: 44.1%
• Matchup: Dallas vs. Portland (10:30PM ET)

Our model has uncovered value on Dallas-Portland to finish as a tie after 90 minutes at +143 odds. A 44.1% probability produces a 2.9% edge, making this a strong play for today's MLS action.

New England ML (-110)

• Edge: 2.8%
• Probability: 55.2%
• Matchup: Toronto vs. New England (7:30PM ET)

A 2.8% edge on a 55.2% probability makes New England to win at -110 odds a solid value play in today's Toronto vs. New England matchup.

Houston ML (-125)

• Edge: 2.7%
• Probability: 58.2%
• Matchup: D.C. United vs. Houston (8:30PM ET)

Our model projects value on Houston to win at -125 odds. A 58.2% probability produces a 2.7% edge, making Houston the favorable ML play in today's matchup.

Sporting KC ML (+260)

• Edge: 2.3%
• Probability: 30.1%
• Matchup: Minnesota vs. Sporting KC (8:30PM ET)

Rounding out our top 10 bets, Sporting KC to defeat Minnesota at +260 odds shows a 30.1% probability and a 2.3% edge.

MLS best bets summary: Wednesday, 7/22/2026

As of 5:08AM ET, here are our top MLS bets by edge recommended by our model:

List of upcoming MLS games to bet on [7/22/2026]

• NY Red Bulls vs. Philadelphia (7:30PM ET, Wednesday)
• Vancouver vs. Cincinnati (7:30PM ET, Wednesday)
• Chicago vs. Miami (7:30PM ET, Wednesday)
• Toronto vs. New England (7:30PM ET, Wednesday)
• NY City vs. Columbus (7:30PM ET, Wednesday)
• Atlanta vs. Charlotte (8:15PM ET, Wednesday)
• D.C. United vs. Houston (8:30PM ET, Wednesday)
• Montreal vs. Nashville (8:30PM ET, Wednesday)
• Minnesota vs. Sporting KC (8:30PM ET, Wednesday)
• Seattle vs. Austin (9:30PM ET, Wednesday)
• San Diego FC vs. Colorado (9:30PM ET, Wednesday)
• Dallas vs. Portland (10:30PM ET, Wednesday)
• Salt Lake vs. LAFC (10:30PM ET, Wednesday)
• St Louis City vs. LA Galaxy (10:30PM ET, Wednesday)
• Orlando vs. San Jose (10:30PM ET, Wednesday)

Conclusion

Our MLS best bets are locked and loaded for July 22, 2026, featuring plays such as Miami ML vs. Chicago and Nashville ML. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are based on current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.