Yankees vs. Orioles Prediction and Odds - May 16, 2022

MLB action continues on Monday at 7:05PM ET as the New York Yankees take on the Baltimore Orioles at Oriole Park at Camden Yards.

The Orioles will have Kyle Bradish (1-1, 4.24 ERA) start, pitting him against Luis Severino (2-0, 4.08 ERA) for the Yankees.

Dimers' top betting picks for Yankees vs. Orioles, plus game predictions and best odds, are featured below.

This NY Yankees vs. Baltimore betting preview is presented by PointsBet, which has a great 5x $100 Risk-Free Bets promo for new customers.

Who will win Yankees vs. Orioles?

Using state-of-the-art machine learning and data, Dimers.com has simulated Monday's Yankees-Orioles MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Yankees a 60% chance of defeating the Orioles .

More: Free Betting Guide for Yankees vs. Orioles

Yankees vs. Orioles Game Odds

• Run Line: Orioles +1.5 (-110), Yankees -1.5 (-105)
• Moneyline: Orioles +160, Yankees -179
• Total: Over/Under 7.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Orioles are +1.5 underdogs versus the Yankees, with -110 at Caesars Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at -105.

PointsBet currently has the best moneyline odds for the Orioles at +160, which means you can bet $100 to profit $160, earning a total payout of $260, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Yankees at -179, where you can risk $179 to win $100, for a total payout of $279, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 54% chance of covering the run line, while the 7.5-run Over/Under is a 55% chance of going Over.

More: Free Prop Picks

Best Bets for Yankees vs. Orioles

• Run Line: Orioles +1.5 @ -110 via Caesars Sportsbook (54% probability)
• Moneyline: Orioles @ +160 via PointsBet (1.8% edge)
• Total: Over 7.5 @ -110 via FanDuel Sportsbook (55% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays every day of the year.

While the Yankees are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option because of the 1.8% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers is pivotal to being profitable in the long run.

Yankees vs. Orioles Betting Guide

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. Baltimore, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Monday's Yankees-Orioles matchup, including pregame predictions, computer picks, and live updates.

Remember, DimersBOT updates frequently, so keep checking this page for the latest betting analysis before Yankees vs. Orioles on Monday May 16, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Yankees vs. Orioles 2022 Game Info

Monday's matchup between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to begin at 7:05PM ET.

• Date: Monday May 16, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Oriole Park at Camden Yards

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Want more MLB predictions like this?

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That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets, which allows us to produce the most reliable MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not see for yourself?

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.