White Sox vs. Yankees Prediction and Odds - May 20, 2022

The New York Yankees face the Chicago White Sox in MLB action at Yankee Stadium on Friday, starting at 7:05PM ET.

The Yankees will have Nestor Cortes (2-1, 1.35 ERA) start, pitting him against Dallas Keuchel (2-3, 5.54 ERA) for the White Sox.

Dimers' best betting picks for White Sox vs. Yankees, as well as game predictions and best odds, are detailed below.

Today's CHI White Sox vs. NY Yankees betting preview is brought to you by PointsBet, which has an awesome 5x $100 Risk-Free Bets promo for new users.

Who will win White Sox vs. Yankees?

Using cutting-edge computer power and data, Dimers.com has simulated Friday's White Sox-Yankees MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Yankees a 64% chance of defeating the White Sox .

More: Free Betting Guide for White Sox vs. Yankees

White Sox vs. Yankees Odds

• Run Line: Yankees -1.5 (-105), White Sox +1.5 (-110)
• Moneyline: Yankees -210, White Sox +185
• Total: Over/Under 8.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Yankees are -1.5 favorites versus the White Sox, with -105 at FanDuel Sportsbook the best odds currently available.

For the underdog White Sox (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -110.

DraftKings Sportsbook currently has the best moneyline odds for the Yankees at -210, which means you can risk $210 to win $100, for a total payout of $310, if they get the W.

Meanwhile, BetMGM currently has the best moneyline odds for the White Sox at +185, where you can bet $100 to profit $185, earning a total payout of $285, if they win.

The Over/Under sits at 8.5 with PointsBet, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) are a 54% chance of covering the run line, while the 8.5-run Over/Under is a 54% chance of going Over.

More: Free Prop Picks

Best Bets for White Sox vs. Yankees

• Run Line: White Sox +1.5 @ -110 via Caesars Sportsbook (54% probability)
• Moneyline: White Sox @ +185 via BetMGM (1.2% edge)
• Total: Over 8.5 @ -110 via PointsBet (54% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in the USA.

While the Yankees are more likely to win the game, according to DimersBOT, taking the White Sox moneyline is the best option because of the 1.2% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being profitable in the long run.

White Sox vs. Yankees Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. NY Yankees, and click or tap on See Matchup for more.

Dimers has full coverage of Friday's White Sox-Yankees matchup, including pregame predictions, free picks, and live scores.

Don't forget, DimersBOT updates frequently, so check this page for the latest betting analysis ahead of White Sox vs. Yankees on Friday May 20, 2022.

Best Betting Offer for White Sox vs. Yankees

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

White Sox vs. Yankees 2022 Game Info

Friday's action between the Yankees and White Sox at Yankee Stadium is scheduled to commence at 7:05PM ET.

• Date: Friday May 20, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Yankee Stadium

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Want more MLB analysis like this?

So, you liked our White Sox vs. Yankees betting predictions? Awesome. Did you know our MLB Betting News section has a detailed betting preview for every MLB matchup as soon as the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets, which allows us to produce the most accurate MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not see for yourself?

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.