White Sox vs. Tigers Prediction and Odds - Sep 16, 2022

The Detroit Tigers take on the Chicago White Sox in MLB action at Comerica Park on Friday, beginning at 7:10PM ET.

Matt Manning (2-2, 3.73 ERA) will get the ball for the Tigers, while the White Sox are going with Lucas Giolito (10-9, 5.18 ERA).

Dimers' top betting picks for White Sox vs. Tigers, as well as game predictions and betting odds, are detailed in this article.

Who will win White Sox vs. Tigers?

Using trusted machine learning and data, Dimers.com has simulated Friday's White Sox-Tigers MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the White Sox a 58% chance of getting the W against the Tigers.

More: Full Betting Analysis for White Sox vs. Tigers

White Sox vs. Tigers Game Odds

• Run Line: Tigers +1.5 (-130), White Sox -1.5 (+115)
• Moneyline: Tigers +130, White Sox -150
• Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Tigers are currently +1.5 underdogs versus the White Sox, with -130 at Caesars Sportsbook the best odds currently available.

For the favored White Sox (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +115.

DraftKings Sportsbook currently has the best moneyline odds for the Tigers at +130. That means you can bet $100 to profit $130, earning a total payout of $230, if they win.

Meanwhile, DraftKings Sportsbook also has the best moneyline odds for the White Sox at -150, where you can risk $150 to win $100, for a total payout of $250, if they come out on top.

The Over/Under for total runs scored is set at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, check out all of the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Tigers (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 7.5 runs is a 57% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for White Sox vs. Tigers

• Run Line: White Sox -1.5 @ +115 via DraftKings Sportsbook
• Moneyline: Tigers @ +130 via DraftKings Sportsbook
• Total: Over 7.5 @ -115 via FanDuel Sportsbook (57% probability)

Our best bets are based on world-class simulations and gambling intelligence to serve you the best possible plays every time.

Although the Tigers are more likely to cover the run line, our best bet of White Sox -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

And while the White Sox are more likely to win the game, according to DimersBOT, betting on the Tigers moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is one of the keys to being profitable in the long run.

White Sox vs. Tigers Prediction

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Dimers has full betting coverage of Friday's White Sox-Tigers matchup, including pregame predictions, best betting picks, and live updates.

Don't forget, DimersBOT updates frequently, so keep checking this article for the latest betting analysis ahead of White Sox vs. Tigers on Friday September 16, 2022.

White Sox vs. Tigers 2022 Game Info

Friday's matchup between the Tigers and White Sox at Comerica Park is scheduled to begin at 7:10PM ET.

• Who: Chicago White Sox vs. Detroit Tigers
• Date: Friday September 16, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Comerica Park

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It's only a click away, so why not take a look around?

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.