White Sox vs. Guardians Prediction for MLB Wednesday [5/24/23]

White Sox vs. Guardians Prediction for MLB Wednesday [5/24/23]

MLB action continues on Wednesday at 1:10PM ET as the Chicago White Sox square off with the Cleveland Guardians at Progressive Field.

The Guardians will have Cal Quantrill (2-2, 4.06 ERA) start, while the White Sox are going with Michael Kopech (2-4, 4.83 ERA).

Dimers' top betting picks for White Sox vs. Guardians, as well as game predictions and betting odds, are detailed in this article.


Who Will Win: White Sox vs. Guardians

Based on advanced computer power and data, Dimers.com has simulated Wednesday's White Sox-Guardians MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Guardians a 52% chance of winning against the White Sox.

More: White Sox vs. Guardians Simulated 10,000 Times

White Sox vs. Guardians Current Odds

  • Run Line: Guardians -1.5 (+146), White Sox +1.5 (-170)
  • Moneyline: Guardians -138, White Sox +120
  • Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Guardians are -1.5 favorites against the White Sox, with +146 at FanDuel Sportsbook the best odds currently available.

For the underdog White Sox (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -170.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -138. That means you can risk $138 to win $100, for a total payout of $238, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the White Sox at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under is set at 7.5 with PointsBet, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) have a 64% chance of covering the run line, while the Over/Under total of 7.5 runs has a 58% chance of going Over.

More: Free Prop Picks

Best Bets for White Sox vs. Guardians


Every time you see a 🔥, you know it's one of our best free picks today across any sport.

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays 24/7.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the White Sox moneyline is the best option due to the 2.2% edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability as a bettor.

White Sox vs. Guardians Prediction

Click or tap on See Matchup for more.


Dimers has full coverage of Wednesday's White Sox-Guardians matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so check this page for any changes to our betting analysis before White Sox vs. Guardians on Wednesday May 24, 2023.


White Sox vs. Guardians 2023

Wednesday's game between the Guardians and White Sox at Progressive Field is scheduled to start at 1:10PM ET.

  • Who: Chicago White Sox vs. Cleveland Guardians
  • Date: Wednesday May 24, 2023
  • Time: 1:10PM ET / 10:10AM PT
  • Venue: Progressive Field

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Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our White Sox vs. Guardians predictions can help you make informed decisions, it's important that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More MLB Analysis Like This?

So, you liked our White Sox vs. Guardians betting predictions? Awesome. Did you know our MLB Betting News section has a comprehensive betting preview for every MLB matchup as soon as the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets. This allows us to write the most reliable MLB betting previews and get the jump on the public and the sportsbooks.

In addition to MLB picks and predictions, we also provide the best MLB prop bets for today, projecting home runs, RBIs, and more against the best odds available every day of the MLB season.

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities compared to the best odds on the market.

Kevin Hansen
Senior Sports Analyst

Kevin Hansen has a track record of delivering high-quality content. He writes about all sports, but his favorites are the NFL, NBA, MLB, and NHL. Kevin enjoys crunching the numbers and using data-driven insights to take on the sportsbooks. The majority of Kevin's time is spent writing about sports betting. His love for data and analytics drove him into the world of sports betting. Finding an edge in sports betting can take a long time, but Kevin believes it is well worth the effort. Kevin is just as passionate about sports as you are, and he empowers fellow bettors to become more educated through simple, actionable betting tips. It can be difficult to navigate the world of sports betting, which is where Kevin comes in to make it as simple as possible for you to pick a winner.

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