White Sox vs. Guardians Prediction and Odds - Jul 13, 2022

The Cleveland Guardians take on the Chicago White Sox in MLB action at Progressive Field on Wednesday, starting at 7:10PM ET.

Aaron Civale (2-5, 6.28 ERA) will start for the Guardians, up against Lucas Giolito (5-5, 5.05 ERA) for the White Sox.

Dimers' free betting picks for White Sox vs. Guardians, plus game predictions and betting odds, are detailed below.

Who will win White Sox vs. Guardians?

Using advanced machine learning and data, Dimers.com has simulated Wednesday's White Sox-Guardians MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently can't split the two teams, giving both the White Sox and Guardians a 50% chance of winning the game.

More: White Sox vs. Guardians Simulated 10K Times

White Sox vs. Guardians Odds

• Run Line: Guardians +1.5 (-164), White Sox -1.5 (+140)
• Moneyline: Guardians +106, White Sox -120
• Total: Over/Under 8 (+100/-110)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs versus the White Sox, with -164 at Caesars Sportsbook the best odds currently available.

For the favored White Sox (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +140.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at +106, which means you can throw down $100 to profit $106, earning a total payout of $206, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the White Sox at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under is set at 8 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 63% chance of covering the run line, while the 8-run Over/Under is a 54% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for White Sox vs. Guardians

• Run Line: Guardians +1.5 @ -164 via Caesars Sportsbook (63% probability)
• Moneyline: Guardians @ +106 via FanDuel Sportsbook (50% probability)
• Total: Over 8 @ +100 via Caesars Sportsbook (54% probability)

Our best bets are based on world-class modeling and betting expertise to help you make better investments with the legal sportsbooks in your state.

White Sox vs. Guardians Prediction

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Cleveland, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's White Sox-Guardians matchup, including pregame predictions, free picks, and live scores.

Remember, DimersBOT updates frequently, so keep an eye on this page for any changes to our betting analysis before White Sox vs. Guardians on Wednesday July 13, 2022.

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White Sox vs. Guardians 2022 Game Info

Wednesday's matchup between the Guardians and White Sox at Progressive Field is scheduled to commence at 7:10PM ET.

• Who: Cleveland Guardians vs. Chicago White Sox
• Date: Wednesday July 13, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Progressive Field

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