Twins vs. Guardians Prediction and Odds - Sep 18, 2022

The Cleveland Guardians face the Minnesota Twins in MLB action at Progressive Field on Sunday, starting at 1:40PM ET.

The Guardians will send Cody Morris (0-1, 2.79 ERA) to the mound, up against Joe Ryan (11-8, 3.83 ERA) for the Twins.

Dimers' free betting picks for Twins vs. Guardians, as well as game predictions and betting odds, are featured below.

Who will win Twins vs. Guardians?

Using state-of-the-art machine learning and data, Dimers.com has simulated Sunday's Twins-Guardians MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Guardians a 53% chance of beating the Twins.

More: Full Betting Guide for Twins vs. Guardians

Twins vs. Guardians Current Odds

• Run Line: Guardians +1.5 (-170), Twins -1.5 (+150)
• Moneyline: Guardians -108, Twins -108
• Total: Over/Under 8 (+100/-110)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs versus the Twins, with -170 at FanDuel Sportsbook the best odds currently available.

For the favored Twins (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +150.

In a sign of how close this game is expected to be, both the Guardians and Twins are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -108, which means you can risk $108 to win $100, for a total payout of $208, if they get the W.

On the other hand, FanDuel Sportsbook also has the best moneyline odds for the Twins at -108, where you can risk $108 to win $100, for a total payout of $208, if they come out on top.

The Over/Under for total runs scored is set at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 65% chance of covering the run line, while the 8-run Over/Under is a 51% chance of going Over.

More: Free Prop Picks

Best Bets for Twins vs. Guardians

• Run Line: Guardians +1.5 @ -170 via FanDuel Sportsbook (65% probability)
• Moneyline: Guardians @ -108 via FanDuel Sportsbook (53% probability)
• Total: Over 8 @ +100 via DraftKings Sportsbook (51% probability)

Our best bets are based on detailed modeling and wagering intelligence to help you make smarter investments with the legal sportsbooks in America.

Twins vs. Guardians Prediction

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Dimers has full betting coverage of Sunday's Twins-Guardians matchup, including pregame predictions, free betting picks, and live updates.

Don't forget, DimersBOT updates often, so check this article for any changes to our betting analysis ahead of Twins vs. Guardians on Sunday September 18, 2022.

Twins vs. Guardians 2022 Game Info

Sunday's game between the Guardians and Twins at Progressive Field is scheduled to start at 1:40PM ET.

• Who: Minnesota Twins vs. Cleveland Guardians
• Date: Sunday September 18, 2022
• Time: 1:40PM ET / 10:40AM PT
• Venue: Progressive Field

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Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

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