MLB- More Betting
Tigers vs. Red Sox Prediction and Odds - Jun 21, 2022

The Boston Red Sox square off with the Detroit Tigers in MLB action at Fenway Park on Tuesday, starting at 7:10PM ET.
The Red Sox will send Rich Hill (2-4, 4.42 ERA) to the mound, while the Tigers will counter with Beau Brieske (1-5, 3.79 ERA).
Dimers' top betting picks for Tigers vs. Red Sox, plus game predictions and betting odds, are detailed below.
Who will win Tigers vs. Red Sox?
Based on trusted machine learning and data, Dimers.com has simulated Tuesday's Tigers-Red Sox MLB matchup 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, gives the Red Sox a 64% chance of getting the W against the Tigers.
More: Tigers vs. Red Sox Simulated 10,000 Times
Tigers vs. Red Sox Odds
- Run Line: Red Sox -1.5 (+105), Tigers +1.5 (-110)
- Moneyline: Red Sox -189, Tigers +170
- Total: Over/Under 9 (-120/+100)
Run Line, Moneyline and Over/Under
The Red Sox are -1.5 favorites versus the Tigers, with +105 at DraftKings Sportsbook the best odds currently available.
For the underdog Tigers (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -110.
Caesars Sportsbook currently has the best moneyline odds for the Red Sox at -189, which means you can risk $189 to win $100, for a total payout of $289, if they get the W.
Elsewhere, PointsBet currently has the best moneyline odds for the Tigers at +170, where you can bet $100 to profit $170, earning a total payout of $270, if they win.
The Over/Under for total runs scored sits at 9 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.
As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.
According to DimersBOT, the Tigers (+1.5) are a 52% chance of covering the run line, while the 9-run Over/Under is a 56% chance of going Over.
More: Free Prop Picks
Best Bets for Tigers vs. Red Sox
- Run Line: Tigers +1.5 @ -110 via FanDuel Sportsbook (52% probability)
- Moneyline: Red Sox @ -189 via Caesars Sportsbook (64% probability)
- Total: Over 9 @ -120 via BetMGM (56% probability)
Dimers' best bets are based on complex simulations and betting intelligence to bring you the best possible plays 24/7/365.
Tigers vs. Red Sox Prediction
Use our widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Detroit vs. Boston, and click or tap on See Matchup for more.
Dimers has full betting coverage of Tuesday's Tigers-Red Sox matchup, including pregame predictions, best betting picks, and live win probabilities.
Don't forget, DimersBOT updates often, so refresh this page for the latest betting analysis ahead of Tigers vs. Red Sox on Tuesday June 21, 2022.
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Tigers vs. Red Sox 2022 Game Info
Tuesday's game between the Red Sox and Tigers at Fenway Park is scheduled to start at 7:10PM ET.
- Who: Boston Red Sox vs. Detroit Tigers
- Date: Tuesday June 21, 2022
- Time: 7:10PM ET / 4:10PM PT
- Venue: Fenway Park
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What other MLB games are on today?
The Tigers and Red Sox aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB game via our MLB Predictions section.
Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out today!
Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.
