Men's CBB- More Betting
St. John's vs. Villanova CBB Prediction and Odds - Dec 21, 2022

Villanova and St. John's clash in College Basketball action at The William B. Finneran Pavilion on Wednesday, with tipoff at 6:30PM ET.
Dimers' best betting picks for St. John's vs. Villanova, plus game predictions and best odds, are featured in this article.
Who will win St. John's vs. Villanova?
Using advanced computer power and data, Dimers.com has simulated Wednesday's St. John's-Villanova College Basketball game 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, gives Villanova a 67% chance of defeating St. John's.
More: St. John's vs. Villanova Simulated 10K Times
St. John's vs. Villanova Game Odds
- Spread: Villanova -5 (-110), St. John's +5 (-110)
- Moneyline: Villanova -210, St. John's +180
- Total: Over/Under 146 (-110/-110)
Point Spread, Moneyline and Over/Under
Villanova is listed as the -5 favorite against St. John's, with -110 at PointsBet the best odds currently available.
For the underdog St. John's (+5) to cover the spread, PointsBet also has the best odds currently on the market at -110.
PointsBet currently has the best moneyline odds for Villanova at -210, which means you can risk $210 to win $100, for a total payout of $310, if it gets the W.
Meanwhile, BetMGM currently has the best moneyline odds for St. John's at +180, where you can bet $100 to profit $180, earning a total payout of $280, if it wins.
The Over/Under sits at 146 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.
As always, check out all of the legal sportbooks available in your state for the best College Basketball odds and lines.
According to DimersBOT, Villanova (-5) is a 52% chance of covering the spread, while the 146-point Over/Under is a 51% chance of going Over.
More: Free Prop Picks
Best Bets for St. John's vs. Villanova
- Spread: Villanova -5 @ -110 via PointsBet (52% probability)
- Moneyline: Villanova @ -210 via PointsBet (67% probability)
- Total: Over 146 @ -110 via PointsBet (51% probability)
Dimers' best bets are based on world-class simulations and betting intelligence to help you make more informed investments with the legal sportsbooks in America.
St. John's vs. Villanova Prediction
Dimers.com's predicted final score for St. John's vs. Villanova at The William B. Finneran Pavilion on Wednesday has Villanova winning 75-70.
Click or tap on See Matchup to reveal more.
Dimers has full betting coverage of Wednesday's St. John's-Villanova matchup, including pregame predictions, free picks, and live win probabilities.
Remember, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis before St. John's vs. Villanova on Wednesday December 21, 2022.
St. John's vs. Villanova 2022 CBB Game Info
Wednesday's game between Villanova and St. John's in College Basketball at The William B. Finneran Pavilion is scheduled to begin at 6:30PM ET.
- Who: St. John's vs. Villanova
- Date: Wednesday December 21, 2022
- Time: 6:30PM ET / 3:30PM PT
- Venue: The William B. Finneran Pavilion
Want to join an online sportsbook and start betting on College Basketball? Check out the top sportsbook offers in your state.
Want more College Basketball predictions like this?
So, you liked our St. John's vs. Villanova betting analysis? Awesome. Did you know our College Basketball Betting News section has a detailed betting preview for every CBB matchup as soon as the sportsbooks release their odds?
That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets, which allows us to produce the most reliable CBB betting previews and get the jump on the public and the sportsbooks.
It's only a click away, so why not see for yourself?
Finally, Dimers' CBB Futures page is our in-house approach to revealing who will win March Madness 2022, with our data-led probabilities compared to the best odds on the market.
