Southern Illinois vs. Southeast Missouri State CBB Prediction and Odds - Dec 21, 2022

College Basketball action continues on Wednesday at 7:30PM ET as the favored Southern Illinois squares off with Southeast Missouri State at Show Me Center.

Dimers' free betting picks for Southern Illinois vs. Southeast Missouri State, as well as game predictions and best odds, are featured below.

Who will win Southern Illinois vs. Southeast Missouri State?

Based on high-tech machine learning and data, Dimers.com has simulated Wednesday's Southern Illinois-Southeast Missouri State College Basketball matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives Southern Illinois a 74% chance of winning against Southeast Missouri State.

More: Free Betting Guide for Southern Illinois vs. Southeast Missouri State

Southern Illinois vs. Southeast Missouri State Game Odds

• Spread: Southeast Missouri State +7.5 (-106), Southern Illinois -7.5 (-110)
• Moneyline: Southeast Missouri State +280, Southern Illinois -320
• Total: Over/Under 136.5 (-110/-110)

Point Spread, Moneyline and Over/Under

Southeast Missouri State is currently the +7.5 underdog versus Southern Illinois, with -106 at FanDuel Sportsbook the best odds currently available.

For the favored Southern Illinois (-7.5) to cover the spread, PointsBet has the best odds currently on the market at -110.

FanDuel Sportsbook currently has the best moneyline odds for Southeast Missouri State at +280, which means you can bet $100 to profit $280, earning a total payout of $380, if it wins.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for Southern Illinois at -320, where you can risk $320 to win $100, for a total payout of $420, if it comes out on top.

The Over/Under for total points scored is set at 136.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, Southeast Missouri State (+7.5) is a 55% chance of covering the spread, while the 136.5-point Over/Under is a 53% chance of going Over.

More: Free Prop Picks

Best Bets for Southern Illinois vs. Southeast Missouri State

• Spread: Southeast Missouri State +7.5 @ -106 via FanDuel Sportsbook (55% probability)
• Moneyline: Southeast Missouri State @ +280 via FanDuel Sportsbook
• Total: Over 136.5 @ -110 via PointsBet (53% probability)

Dimers' best bets are based on detailed simulations and betting expertise to bring you the best possible plays every time.

While Southern Illinois is more likely to win the game, according to DimersBOT, betting on Southeast Missouri State moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is one of the keys to achieving long-term profitability as a sports bettor.

Southern Illinois vs. Southeast Missouri State Prediction

Dimers.com's predicted final score for Southern Illinois vs. Southeast Missouri State at Show Me Center on Wednesday has Southern Illinois winning 72-65.

Click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Southern Illinois-Southeast Missouri State matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep an eye on this page for the latest betting insights before Southern Illinois vs. Southeast Missouri State on Wednesday December 21, 2022.

Southern Illinois vs. Southeast Missouri State 2022 CBB Game Info

Wednesday's game between Southeast Missouri State and Southern Illinois in College Basketball at Show Me Center is scheduled to begin at 7:30PM ET.

• Who: Southern Illinois vs. Southeast Missouri State
• Date: Wednesday December 21, 2022
• Time: 7:30PM ET / 4:30PM PT
• Venue: Show Me Center

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What other CBB games are on tonight?

Southern Illinois and Southeast Missouri State aren't the only two NCAA Basketball teams you can bet on tonight. DimersBOT never stops and we've got picks and best bets for each and every CBB matchup in our College Basketball Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' CBB Futures page is our in-house approach to revealing who will win March Madness 2022, with our data-led probabilities paired with the best odds to win the NCAA Tournament.