San Francisco 49ers vs. Washington Commanders Prediction, Odds, NFL Picks - Week 17 [2023]

San Francisco 49ers vs. Washington Commanders Prediction, Odds, NFL Picks - Week 17 [2023]

The Washington Commanders and San Francisco 49ers are scheduled to meet in Week 17 of the NFL season at FedExField on Sunday, starting at 1:00PM ET.'s in-depth betting preview for this week's 49ers vs. Commanders matchup includes the latest betting odds, as well as our predictions and picks for the game.

49ers vs. Commanders Prediction: Who Will Win, Cover the Spread

We have used advanced machine learning and data analysis to simulate the result of Sunday's NFL game between the 49ers and Commanders 10,000 times, in keeping with our coverage of NFL predictions.

Our leading predictive analytics model currently gives the 49ers an 81% chance of beating the Commanders in Week 17 of the NFL season, and our predicted final score has the 49ers winning 29-19.

According to our model, the Commanders (+13) have a 56% chance of covering the spread, while the Over/Under total of 50 points has a 53% chance of going under.

This San Francisco vs. Washington betting preview is proudly sponsored by Bet365, which has a great Bet $5, Get $150 in Bonus Bets promo for new customers.

49ers vs. Commanders Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type 49ers Commanders
Spread -13 (-110) +13 (-110)
Moneyline -750 +575
Total o50 (-110) u50 (-110)
  • The Commanders are currently +13 underdogs versus the 49ers, with -110 at BetMGM Sportsbook the best odds currently available.
  • For the favored 49ers (-13) to cover the spread, BetMGM also has the best odds currently on offer at -110.
  • BetMGM currently has the best moneyline odds for the Commanders at +575, which means you can bet $100 to profit $575, earning a total payout of $675, if they win.
  • Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the 49ers at -750, where you can risk $750 to win $100 for a total payout of $850 if they come out on top.
  • The Over/Under sits at 50 with DraftKings, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

All odds are correct at the time of publication and are subject to change.

As always, check out all the online sportsbooks available in your state for the best NFL odds and lines.

49ers vs. Commanders Picks

By comparing our predictions to the odds listed above, we have found the best betting picks for this game:

Bet Type Our Pick Best Odds
Spread Commanders +13 -110
Moneyline Commanders +575 πŸ”₯
Total Under 50 -110


Any time you see a πŸ”₯, you know it's one of Dimers' best bets of the day across any sport.

While the 49ers are more likely to win the game, taking the Commanders moneyline is the best option due to the 4.1% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers is pivotal to achieving long-term profitability.

Our best NFL bets are based on detailed modeling and betting expertise to bring you the best possible plays every week of the season.

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49ers vs. Commanders TD Scorers

Who will score an anytime touchdown in 49ers vs. Commanders?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first TD in 49ers vs. Commanders.

Our projections give McCaffrey a 23.8% chance of scoring the first TD at FedExField, while the 49ers RB is a 78.1% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player First TD Probability
Christian McCaffrey 23.8%
Brandon Aiyuk 10.6%
Deebo Samuel 10.0%
George Kittle 6.9%
Elijah Mitchell 5.2%

Washington Commanders

Player First TD Probability
Brian Robinson 7.2%
Antonio Gibson 5.5%
Terry McLaurin 5.5%
Curtis Samuel 4.4%
Jahan Dotson 4.2%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player Anytime TD Probability
Christian McCaffrey 78.1%
Brandon Aiyuk 47.2%
Deebo Samuel 45.0%
George Kittle 32.4%
Elijah Mitchell 25.3%

Washington Commanders

Player Anytime TD Probability
Brian Robinson 34.4%
Terry McLaurin 28.1%
Antonio Gibson 27.8%
Curtis Samuel 23.2%
Jahan Dotson 22.0%

49ers vs Commanders Player Props

Here, you will find detailed projections for all of the key offensive players from the 49ers and Commanders, including passing, rushing and receiving yards.

49ers vs. Commanders Quarterbacks

Of the starting quarterbacks, the 49ers' Brock Purdy is projected to have a big game with 272 passing yards. The Commanders' Jacoby Brissett is expected to throw for 238 yards.

Player Proj. Pass Yards
Brock Purdy (SF) 272 yds
Jacoby Brissett (WAS) 238 yds

49ers Rushing

Player Proj. Rush Yards
Christian McCaffrey 91 yds
Elijah Mitchell 15 yds
Deebo Samuel 13 yds

Commanders Rushing

Player Proj. Rush Yards
Brian Robinson 48 yds
Jacoby Brissett 20 yds
Antonio Gibson 15 yds

49ers Receiving

Player Proj. Rec. Yards
Brandon Aiyuk 71 yds
Deebo Samuel 56 yds
George Kittle 52 yds
Christian McCaffrey 35 yds
Jauan Jennings 19 yds

Commanders Receiving

Player Proj. Rec. Yards
Terry McLaurin 66 yds
Curtis Samuel 37 yds
Jahan Dotson 34 yds
Antonio Gibson 29 yds
Logan Thomas 25 yds

Don't forget, our model updates regularly, so check this article for the latest betting analysis ahead of the 49ers vs. Commanders on Sunday December 31, 2023.

49ers vs. Commanders Game Information

The NFL Week 17 action between the Commanders and 49ers at FedExField is scheduled to commence at 1:00PM ET.


Our full coverage of 49ers vs. Commanders includes pregame predictions, betting picks, and live win probabilities.

How to Bet on 49ers vs. Commanders

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This preview article has been partially generated using automated processes and AI technology. Our goal is to provide timely and accurate updates on 49ers vs. Commanders Week 14 contest, and automation assists in data collection, analysis, and formatting. Human editing and quality control are performed to ensure the content meets our editorial standards.

Our predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods. While our 49ers vs. Commanders picks can help you make informed decisions, it's crucial that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial relationship with (such as a sportsbook), we may earn a referral fee at no additional cost to you.

More on NFL

Stay informed with the latest NFL news and our data-led NFL picks and parlays all season long. Plus, our Super Bowl odds give you the latest predictions and the best available odds on the Super Bowl, AFC, NFC, and each division.

Ryan Leaver
Senior Sports and Sports Betting Editor

Ryan Leaver has long been entrenched in the world of sports and sports betting, now specializing in the NBA, NFL, college football, college basketball, and soccer. His passion shines through in his detailed game previews, best bets, props, and futures articles for both the NBA and NFL, along with his sharp prop bets for college football and insightful best bets for college basketball. Ryan’s expertise also extends to soccer, where he frequently offers practical betting tips and highlights the bets of the day. 

Known for his keen eye for valuable betting promos, Ryan adeptly guides bettors toward opportunities that enhance their wagering experiences. Collaborating often with DimersBOT, his articles are meticulously researched and offer savvy betting advice, making him a trusted source for sports bettors.

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