Royals vs. Guardians Prediction and Odds - Jun 1, 2022

The Cleveland Guardians square off with the Kansas City Royals in MLB action at Progressive Field on Wednesday, starting at 1:10PM ET.

The Guardians will have Konnor Pilkington (0-0, 3.75 ERA) start, up against Brad Keller (1-5, 3.95 ERA) for the Royals.

Dimers' best betting picks for Royals vs. Guardians, as well as game predictions and best odds, are featured in this article.

Who will win Royals vs. Guardians?

Using state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Royals-Guardians MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Guardians a 60% chance of beating the Royals.

More: Full Betting Guide for Royals vs. Guardians

Royals vs. Guardians Current Odds

• Run Line: Guardians -1.5 (+140), Royals +1.5 (-155)
• Moneyline: Guardians -140, Royals +120
• Total: Over/Under 9 (-118/+100)

Run Line, Moneyline and Over/Under

The Guardians are -1.5 favorites versus the Royals, with +140 at PointsBet the best odds currently available.

For the underdog Royals (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -155.

PointsBet currently has the best moneyline odds for the Guardians at -140, which means you can risk $140 to win $100, for a total payout of $240, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Royals at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under sits at 9 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 57% chance of covering the run line, while the Over/Under total of 9 runs is a 51% chance of going Under.

More: Free Prop Picks

Best Bets for Royals vs. Guardians

• Run Line: Guardians -1.5 @ +140 via PointsBet (0.9% edge)
• Moneyline: Guardians @ -140 via PointsBet (60% probability)
• Total: Under 9 @ +100 via BetMGM (51% probability)

Dimers' best bets are based on complex simulations and betting intelligence to bring you the best possible plays 24/7.

Even though the Royals are more likely to cover the run line, our best bet of Guardians -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Royals vs. Guardians Betting Guide

Use our widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Kansas City vs. Cleveland, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Royals-Guardians matchup, including pregame predictions, top betting picks, and live scores.

Remember, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before Royals vs. Guardians on Wednesday June 1, 2022.

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Royals vs. Guardians 2022 Game Info

Wednesday's matchup between the Guardians and Royals at Progressive Field is scheduled to start at 1:10PM ET.

• Who: Cleveland Guardians vs. Kansas City Royals
• Date: Wednesday June 1, 2022
• Time: 1:10PM ET / 10:10AM PT
• Venue: Progressive Field

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Want more MLB predictions like this?

So, you liked our Royals vs. Guardians betting analysis? Awesome. Did you know our MLB Betting News page has a detailed betting preview for every MLB matchup the second the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets. This allows us to create the most reliable MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.