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Reds vs. Cardinals Prediction and Odds - Sep 15, 2022

MLB action continues on Thursday at 7:45PM ET as the Cincinnati Reds take on the St. Louis Cardinals at Busch Stadium.
The Cardinals will send Miles Mikolas (11-11, 3.42 ERA) to the mound, while the Reds are going with Chase Anderson (0-3, 9.00 ERA).
Dimers' best betting picks for Reds vs. Cardinals, as well as game predictions and betting odds, are detailed below.
Who will win Reds vs. Cardinals?
Based on advanced computer power and data, Dimers.com has simulated Thursday's Reds-Cardinals MLB game 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, currently gives the Cardinals a 69% chance of defeating the Reds.
More: Reds vs. Cardinals Simulated 10K Times
Reds vs. Cardinals Game Odds
- Run Line: Cardinals -1.5 (-138), Reds +1.5 (+125)
- Moneyline: Cardinals -275, Reds +245
- Total: Over/Under 8 (-110/-105)
Run Line, Moneyline and Over/Under
The Cardinals are currently -1.5 favorites against the Reds, with -138 at FanDuel Sportsbook the best odds currently available.
For the underdog Reds (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +125.
BetMGM currently has the best moneyline odds for the Cardinals at -275. That means you can risk $275 to win $100, for a total payout of $375, if they get the W.
Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Reds at +245, where you can put down $100 to profit $245, earning a total payout of $345, if they win.
The Over/Under for total runs scored sits at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at -105.
As always, check out all of the legal sportbooks that are available in your state for the best MLB odds and lines.
According to DimersBOT, the Cardinals (-1.5) are a 53% chance of covering the run line, while the Over/Under total of 8 runs is a 55% chance of going Over.
More: Best Prop Bets to Make Today
Best Bets for Reds vs. Cardinals
- Run Line: Reds +1.5 @ +125 via DraftKings Sportsbook (2.1% edge)
- Moneyline: Reds @ +245 via FanDuel Sportsbook (1.9% edge)
- Total: Over 8 @ -110 via Caesars Sportsbook (55% probability)
Our best bets are based on world-class modeling and betting expertise to serve you the best possible plays every day of the year.
Although the Cardinals are more likely to cover the run line, our best bet of Reds +1.5 is based on the likelihood of that happening, according to DimersBOT, and the top odds available.
And while the Cardinals are more likely to win the game, according to DimersBOT, betting on the Reds moneyline is the best option due to the 1.9% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.
Taking advantage of the edges seen here at Dimers is pivotal to achieving long-term profitability as a bettor.
Reds vs. Cardinals Prediction
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Dimers has full betting coverage of Thursday's Reds-Cardinals matchup, including pregame predictions, free betting picks, and live win probabilities.
Remember, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis ahead of Reds vs. Cardinals on Thursday September 15, 2022.
Reds vs. Cardinals 2022 Game Info
Thursday's action between the Cardinals and Reds at Busch Stadium is scheduled to begin at 7:45PM ET.
- Who: Cincinnati Reds vs. St. Louis Cardinals
- Date: Thursday September 15, 2022
- Time: 7:45PM ET / 4:45PM PT
- Venue: Busch Stadium
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