Phillies vs. Astros Prediction and Odds - Oct 5, 2022

The Houston Astros take on the Philadelphia Phillies in MLB action at Minute Maid Park on Wednesday, beginning at 4:10PM ET.

Framber Valdez (16-6, 2.89 ERA) will be on the bump for the Astros, while the Phillies will counter with Bailey Falter (6-4, 3.90 ERA).

Dimers' top betting picks for Phillies vs. Astros, as well as game predictions and betting odds, are detailed in this article.

Who will win Phillies vs. Astros?

Based on advanced machine learning and data, Dimers.com has simulated Wednesday's Phillies-Astros MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Astros a 67% chance of defeating the Phillies.

More: Phillies vs. Astros Simulated 10,000 Times

Phillies vs. Astros Game Odds

• Run Line: Astros -1.5 (+112), Phillies +1.5 (-120)
• Moneyline: Astros -195, Phillies +170
• Total: Over/Under 7.5 (+100/-115)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites against the Phillies, with +112 at FanDuel Sportsbook the best odds currently available.

For the underdog Phillies (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -120.

DraftKings Sportsbook currently has the best moneyline odds for the Astros at -195, which means you can risk $195 to win $100, for a total payout of $295, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Phillies at +170, where you can bet $100 to profit $170, earning a total payout of $270, if they win.

The Over/Under for total runs scored is set at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while BetMGM currently has the best odds for the Under at -115.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Phillies (+1.5) are a 51% chance of covering the run line, while the 7.5-run Over/Under is a 61% chance of going Over.

More: Free Prop Picks

Best Bets for Phillies vs. Astros

• Run Line: Astros -1.5 @ +112 via FanDuel Sportsbook (1.4% edge)
• Moneyline: Astros @ -195 via DraftKings Sportsbook (67% probability)
• Total: Over 7.5 @ +100 via DraftKings Sportsbook (61% probability) 🔥

If you see a 🔥, that means it's one of our best bets today across all major pro and college sports.

Dimers' best bets are based on world-class simulations and gambling expertise to bring you the best possible plays 24/7/365.

Even though the Phillies are more likely to cover the run line, our best bet of Astros -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Phillies vs. Astros Prediction

Click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Phillies-Astros matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this article for the latest betting analysis ahead of Phillies vs. Astros on Wednesday October 5, 2022.

Phillies vs. Astros 2022 Game Info

Wednesday's matchup between the Astros and Phillies at Minute Maid Park is scheduled to commence at 4:10PM ET.

• Who: Philadelphia Phillies vs. Houston Astros
• Date: Wednesday October 5, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: Minute Maid Park

Ready to join an online sportsbook and start betting on MLB now? We've reviewed the best available welcome offers in each and every legal betting state.

What MLB games are on today?

Now you've got the 411 on Phillies vs. Astros, take a look at the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds on the market.