Padres vs. Yankees Prediction for MLB Friday [5/26/2023]

Padres vs. Yankees Prediction for MLB Friday [5/26/2023]

The New York Yankees and San Diego Padres are scheduled to meet in MLB action at Yankee Stadium on Friday, starting at 7:05PM ET.

The Yankees will send Randy Vásquez (0-0, 0.00 ERA) to the mound, pitting him against Joe Musgrove (1-2, 6.75 ERA) for the Padres.

Dimers' top betting picks for Padres vs. Yankees, as well as game predictions and betting odds, are detailed in this article.


Who Will Win: Padres vs. Yankees

Based on high-tech computer power and data, has simulated Friday's Padres-Yankees MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Padres a 51% chance of defeating the Yankees.

More: Betting Guide for Padres vs. Yankees

Padres vs. Yankees Game Odds

  • Run Line: Yankees +1.5 (-160), Padres -1.5 (+140)
  • Moneyline: Yankees -102, Padres -115
  • Total: Over/Under 10.5 (-105/-125)

Run Line, Moneyline and Over/Under

The Yankees are +1.5 underdogs against the Padres, with -160 at DraftKings Sportsbook the best odds currently available.

For the favored Padres (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +140.

In a sign of how close this game is expected to be, both the Yankees and Padres are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Yankees at -102. That means you can risk $102 to win $100, for a total payout of $202, if they get the W.

Meanwhile, PointsBet currently has the best moneyline odds for the Padres at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under for total runs scored sits at 10.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -105, as well as the best odds for the Under at -125.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Yankees (+1.5) have a 62% chance of covering the run line, while the Over/Under total of 10.5 runs has a 63% chance of going Under.

More: Free Prop Picks

Best Bets for Padres vs. Yankees


When you see a 🔥, you know it's one of our best free picks of the day across any sport.

Dimers' best bets are based on detailed simulations and betting expertise to serve you the best possible plays 24/7.

While the Padres are more likely to win the game, according to DimersBOT, taking the Yankees moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at is one of the keys to being profitable in the long run.

Padres vs. Yankees Prediction

Click or tap on See Matchup for more.


Dimers has full coverage of Friday's Padres-Yankees matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates often, so check this article for the latest betting analysis before Padres vs. Yankees on Friday May 26, 2023.


Padres vs. Yankees 2023

Friday's action between the Yankees and Padres at Yankee Stadium is scheduled to begin at 7:05PM ET.

  • Who: San Diego Padres vs. New York Yankees
  • Date: Friday May 26, 2023
  • Time: 7:05PM ET / 4:05PM PT
  • Venue: Yankee Stadium

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Calling Our Shot ⚾️ Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Padres vs. Yankees picks can help you make informed decisions, it's vital that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More MLB Predictions Like This?

To get more MLB betting previews like you've just read for Padres vs. Yankees, all you've gotta do is visit our MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the best MLB betting previews out there. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – check out our MLB picks and predictions.

In addition to MLB picks and predictions, Dimers also offers the best MLB prop bets for today, projecting home runs, RBIs, and more against the top odds available every day of the MLB season.

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the World Series, with our data-led probabilities matched against the best odds to win the World Series.

Kevin Hansen
Senior Sports Analyst

Kevin Hansen has a track record of delivering high-quality content. He writes about all sports, but his favorites are the NFL, NBA, MLB, and NHL. Kevin enjoys crunching the numbers and using data-driven insights to take on the sportsbooks. The majority of Kevin's time is spent writing about sports betting. His love for data and analytics drove him into the world of sports betting. Finding an edge in sports betting can take a long time, but Kevin believes it is well worth the effort. Kevin is just as passionate about sports as you are, and he empowers fellow bettors to become more educated through simple, actionable betting tips. It can be difficult to navigate the world of sports betting, which is where Kevin comes in to make it as simple as possible for you to pick a winner.

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