Padres vs. Phillies Prediction and Odds - May 18, 2022

The Philadelphia Phillies and San Diego Padres clash in MLB at Citizens Bank Park on Wednesday, starting at 6:45PM ET.

The Phillies will have Zack Wheeler (1-3, 4.26 ERA) start, while the Padres are going with Blake Snell (0-0, 0.00 ERA).

Dimers' top betting picks for Padres vs. Phillies, plus game predictions and best odds, are detailed below.

This San Diego vs. Philadelphia betting preview is brought to you by PointsBet, which has a 5x $100 Risk-Free Bets offer for new users.

Who will win Padres vs. Phillies?

Using high-tech computer power and data, Dimers.com has simulated Wednesday's Padres-Phillies MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Phillies a 58% chance of beating the Padres .

More: Padres vs. Phillies Simulated 10,000 Times

Padres vs. Phillies Game Odds

• Run Line: Phillies -1.5 (+146), Padres +1.5 (-155)
• Moneyline: Phillies -149, Padres +135
• Total: Over/Under 7.5 (+110/-120)

Run Line, Moneyline and Over/Under

The Phillies are -1.5 favorites against the Padres, with +146 at FanDuel Sportsbook the best odds currently available.

For the underdog Padres (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at -155.

Caesars Sportsbook currently has the best moneyline odds for the Phillies at -149, which means you can risk $149 to win $100, for a total payout of $249, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Padres at +135, where you can bet $100 to profit $135, earning a total payout of $235, if they win.

The Over/Under for total runs scored sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at +110, while BetMGM currently has the best odds for the Under at -120.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Padres (+1.5) are a 61% chance of covering the run line, while the 7.5-run Over/Under is a 51% chance of going Over.

More: Free Prop Picks

Best Bets for Padres vs. Phillies

• Run Line: Padres +1.5 @ -155 via DraftKings Sportsbook (61% probability)
• Moneyline: Padres @ +135 via DraftKings Sportsbook
• Total: Over 7.5 @ +110 via Caesars Sportsbook (51% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays 24/7.

While the Phillies are more likely to win the game, according to DimersBOT, betting on the Padres moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published on Dimers.com is crucial to being a profitable sports bettor in the long run.

Padres vs. Phillies Betting Guide

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Diego vs. Philadelphia, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Padres-Phillies matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis before Padres vs. Phillies on Wednesday May 18, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Padres vs. Phillies 2022 Game Info

Wednesday's action between the Phillies and Padres at Citizens Bank Park is scheduled to commence at 6:45PM ET.

• Date: Wednesday May 18, 2022
• Time: 6:45PM ET / 3:45PM PT
• Venue: Citizens Bank Park

Looking to join an online sportsbook and start betting on MLB? Check out the top sports betting offers in your state.

What other MLB games are on today?

The Padres and Phillies aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB game via our MLB Predictions section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.