Padres vs. Cubs Prediction and Odds - Jun 15, 2022

The Chicago Cubs take on the San Diego Padres in MLB action at Wrigley Field on Wednesday, starting at 8:05PM ET.

Caleb Kilian (0-0, 5.40 ERA) will start on the mound for the Cubs, while the Padres will counter with Ryan Weathers (0-0, 0.00 ERA).

Dimers' best betting picks for Padres vs. Cubs, as well as game predictions and betting odds, are featured below.

Who will win Padres vs. Cubs?

Using cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Padres-Cubs MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Cubs a 55% chance of defeating the Padres.

More: Free Betting Guide for Padres vs. Cubs

Padres vs. Cubs Current Odds

• Run Line: Cubs -1.5 (+140), Padres +1.5 (-145)
• Moneyline: Cubs -140, Padres +122
• Total: Over/Under 12 (-105/-105)

Run Line, Moneyline and Over/Under

The Cubs are -1.5 favorites versus the Padres, with +140 at Caesars Sportsbook the best odds currently available.

For the underdog Padres (+1.5) to cover the run line, PointsBet has the best odds currently on offer at -145.

PointsBet currently has the best moneyline odds for the Cubs at -140. That means you can risk $140 to win $100, for a total payout of $240, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Padres at +122, where you can bet $100 to profit $122, earning a total payout of $222, if they win.

The Over/Under for total runs scored sits at 12 with BetMGM, which currently has the best odds for the Over at -105, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, check out all of the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Padres (+1.5) are a 60% chance of covering the run line, while the 12-run Over/Under is a 60% chance of going Under.

More: Best Prop Bets Today

Best Bets for Padres vs. Cubs

• Run Line: Padres +1.5 @ -145 via PointsBet (60% probability)
• Moneyline: Padres @ +122 via FanDuel Sportsbook (0.1% edge)
• Total: Under 12 @ -105 via DraftKings Sportsbook (60% probability) 🔥

If you see a 🔥, you know it's one of Dimers' best free picks today across all sports.

Dimers' best bets are based on world-class modeling and gambling expertise to help you make smarter investments with the legal sportsbooks in America.

While the Cubs are more likely to win the game, according to DimersBOT, betting on the Padres moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers.com is one of the keys to achieving long-term profitability as a sports bettor.

Padres vs. Cubs Betting Guide

Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Diego vs. CHI Cubs, and click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Padres-Cubs matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting analysis ahead of Padres vs. Cubs on Wednesday June 15, 2022.

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Padres vs. Cubs 2022 Game Info

Wednesday's matchup between the Cubs and Padres at Wrigley Field is scheduled to commence at 8:05PM ET.

• Who: Chicago Cubs vs. San Diego Padres
• Date: Wednesday June 15, 2022
• Time: 8:05PM ET / 5:05PM PT
• Venue: Wrigley Field

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What other MLB games are on today?

The Padres and Cubs aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single MLB game via our MLB Predictions page.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.