New York Yankees vs. San Diego Padres Prediction, Odds, MLB Picks [5/25/2024]

New York Yankees vs. San Diego Padres Prediction, Odds, MLB Picks [5/25/2024]

The San Diego Padres and New York Yankees are scheduled to meet in MLB action at PETCO Park on Saturday, starting at 9:40PM ET.

The Padres will start Dylan Cease (5-3, 3.05 ERA), pitting him against Marcus Stroman (3-2, 3.05 ERA) for the Yankees.'s comprehensive preview of Saturday's Yankees vs. Padres matchup includes our prediction, picks and the latest betting odds.

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Yankees vs. Padres Prediction: Who Will Win

We have used advanced machine learning and statistical analysis to simulate the outcome of Saturday's MLB game between the Yankees and Padres 10,000 times, in keeping with our coverage of MLB picks.

Our famous predictive analytics model gives the Padres a 56% chance of defeating the Yankees.

According to our model, the over/under total of 7.5 runs also has a 51% chance of going under.

MORE: NY Sports Betting Revenue Reaches New High in May 2024

Yankees vs. Padres Odds [5/25/2024]

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Yankees Padres
Moneyline +106 -120
Total o7.5 (+104) u7.5 (-128)

All odds are correct at the time of publication and are subject to change.

Yankees vs. Padres Picks

At Dimers, our predictions, coupled with the current odds, reveal the top betting picks for every game, including Yankees vs. Padres. Our MLB best bets are based on expert modeling and analysis, as you can see.

Dimers Pro unlocks +EV bets daily. Through Dimers Pro, we give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join now to find any potential picks for this matchup.


Yankees vs. Padres Game Information

Saturday's MLB matchup between the Padres and Yankees at PETCO Park is scheduled to begin at 9:40PM ET.


Our full betting coverage of the Yankees vs. Padres includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.


We predict the Padres, with a 56% win probability, will likely beat the Yankees on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

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