MLB- More Betting
Nationals vs. Brewers Prediction and Odds - May 21, 2022

MLB action continues on Saturday at 7:10PM ET as the Washington Nationals lock horns with the Milwaukee Brewers at American Family Field.
The Brewers will send Brandon Woodruff (4-2, 5.35 ERA) to the mound, pitting him against Patrick Corbin (0-6, 6.28 ERA) for the Nationals.
Dimers' top betting picks for Nationals vs. Brewers, plus game predictions and best odds, are detailed in this article.
This Washington vs. Milwaukee betting analysis is proudly sponsored by PointsBet, which has a 5x $100 Risk-Free Bets offer for new customers.
Who will win Nationals vs. Brewers?
Based on high-tech machine learning and data, Dimers.com has simulated Saturday's Nationals-Brewers MLB game 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, gives the Brewers a 64% chance of winning against the Nationals .
More: Nationals vs. Brewers Simulated 10,000 Times
Nationals vs. Brewers Game Odds
- Run Line: Brewers -1.5 (+100), Nationals +1.5 (-110)
- Moneyline: Brewers -225, Nationals +200
- Total: Over/Under 7.5 (-115/+100)
Run Line, Moneyline and Over/Under
The Brewers are -1.5 favorites versus the Nationals, with +100 at FanDuel Sportsbook the best odds currently available.
For the underdog Nationals (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -110.
BetMGM currently has the best moneyline odds for the Brewers at -225. That means you can risk $225 to win $100, for a total payout of $325, if they get the W.
Meanwhile, PointsBet currently has the best moneyline odds for the Nationals at +200, where you can bet $100 to profit $200, earning a total payout of $300, if they win.
The Over/Under for total runs scored sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.
As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.
According to DimersBOT, the Nationals (+1.5) are a 55% chance of covering the run line, while the Over/Under total of 7.5 runs is a 51% chance of going Over.
More: Free Prop Picks
Best Bets for Nationals vs. Brewers
- Run Line: Nationals +1.5 @ -110 via Caesars Sportsbook (55% probability)
- Moneyline: Nationals @ +200 via PointsBet (2.8% edge)
- Total: Under 7.5 @ +100 via BetMGM
Dimers' best bets are based on complex simulations and betting intelligence to help you make smarter decisions with the legal sportsbooks in the USA.
While the Brewers are more likely to win the game, according to DimersBOT, betting on the Nationals moneyline is the best option because of the 2.8% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.
Taking advantage of the edges seen on Dimers is one of the keys to achieving long-term profitability.
Furthermore, despite the Over being more likely to hit on this occasion, Under 7.5 is our best bet on account of the better odds (+100) that are available from BetMGM.
Nationals vs. Brewers Probabilities
Use our widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Washington vs. Milwaukee, and click or tap on See Matchup to reveal more.
Dimers has full coverage of Saturday's Nationals-Brewers matchup, including pregame predictions, top betting picks, and live win probabilities.
Remember, DimersBOT updates frequently, so keep an eye on this page for any changes to our betting analysis ahead of Nationals vs. Brewers on Saturday May 21, 2022.
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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.
Nationals vs. Brewers 2022 Game Info
Saturday's action between the Brewers and Nationals at American Family Field is scheduled to commence at 7:10PM ET.
- Date: Saturday May 21, 2022
- Time: 7:10PM ET / 4:10PM PT
- Venue: American Family Field
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What MLB games are on today?
Now you've got the 411 on Nationals vs. Brewers, see the latest betting predictions for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for every single MLB matchup.
Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!
While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.
