Mets vs. Giants Prediction and Odds - May 25, 2022

The San Francisco Giants and New York Mets lock horns in MLB at Oracle Park on Wednesday, starting at 3:45PM ET.

Jakob Junis (1-1, 2.70 ERA) will be on the bump for the Giants, while the Mets are going with Thomas Szapucki (0-0, 0.00 ERA).

Dimers' best betting picks for Mets vs. Giants, plus game predictions and best odds, are featured below.

Today's NY Mets vs. San Francisco betting preview is proudly sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Mets vs. Giants?

Using advanced machine learning and data, Dimers.com has simulated Wednesday's Mets-Giants MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently can't split the two teams, giving both the Mets and Giants a 50% chance of winning the game.

More: Mets vs. Giants Simulated 10,000 Times

Mets vs. Giants Odds

• Run Line: Giants +1.5 (-180), Mets -1.5 (+155)
• Moneyline: Giants -115, Mets +100
• Total: Over/Under 9 (-105/-105)

Run Line, Moneyline and Over/Under

The Giants are +1.5 underdogs against the Mets, with -180 at DraftKings Sportsbook the best odds currently available.

For the favored Mets (-1.5) to cover the run line, DraftKings Sportsbook also has the best odds currently on offer at +155.

Caesars Sportsbook currently has the best moneyline odds for the Giants at -115. That means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Mets at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under for total runs scored is set at 9 with FanDuel Sportsbook, which currently has the best odds for the Over at -105, while PointsBet currently has the best odds for the Under at -105.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 9 runs is considered an equal 50-50 chance of hitting.

More: Free Prop Picks

Best Bets for Mets vs. Giants

• Run Line: Mets -1.5 @ +155 via DraftKings Sportsbook
• Moneyline: Mets @ +100 via BetMGM (50% probability)
• Total: Over 9 @ -105 via FanDuel Sportsbook (50% probability)

Dimers' best bets are based on complex simulations and betting intelligence to help you make smarter decisions with the legal sportsbooks in America.

Even though the Giants are more likely to cover the run line, our best bet of Mets -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Mets vs. Giants Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for NY Mets vs. San Francisco, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Mets-Giants matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for any changes to our betting insights ahead of Mets vs. Giants on Wednesday May 25, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Mets vs. Giants 2022 Game Info

Wednesday's action between the Giants and Mets at Oracle Park is scheduled to start at 3:45PM ET.

• Who: San Francisco Giants vs. New York Mets
• Date: Wednesday May 25, 2022
• Time: 3:45PM ET / 12:45PM PT
• Venue: Oracle Park

Looking to join an online sportsbook and start betting on MLB? Check out the top sports betting offers in your state.

Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Mets vs. Giants, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the most comprehensive MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.