MLB- More Betting
Mets vs. Astros Prediction and Odds - Jun 22, 2022

The Houston Astros face the New York Mets in MLB action at Minute Maid Park on Wednesday, commencing at 2:10PM ET.
The Astros will send Luis Garcia (4-5, 3.54 ERA) to the mound, pitting him against Carlos Carrasco (8-2, 3.96 ERA) for the Mets.
Dimers' best betting picks for Mets vs. Astros, plus game predictions and betting odds, are detailed below.
Who will win Mets vs. Astros?
Based on state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Mets-Astros MLB matchup 10,000 times.
Dimers' famous predictive analytics model, DimersBOT, currently gives the Astros a 57% chance of defeating the Mets.
More: Mets vs. Astros Simulated 10K Times
Mets vs. Astros Game Odds
- Run Line: Astros -1.5 (+152), Mets +1.5 (-165)
- Moneyline: Astros -140, Mets +120
- Total: Over/Under 8 (-110/-105)
Run Line, Moneyline and Over/Under
The Astros are -1.5 favorites versus the Mets, with +152 at FanDuel Sportsbook the best odds currently available.
For the underdog Mets (+1.5) to cover the run line, BetMGM has the best odds currently on the market at -165.
PointsBet currently has the best moneyline odds for the Astros at -140. That means you can risk $140 to win $100, for a total payout of $240, if they get the W.
Elsewhere, BetMGM currently has the best moneyline odds for the Mets at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.
The Over/Under for total runs scored is set at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at -105.
As always, check out all the online sportsbooks that are available in your state for the best MLB odds and lines.
According to DimersBOT, the Mets (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 8 runs is a 54% chance of going Over.
More: Best Prop Bets Today
Best Bets for Mets vs. Astros
- Run Line: Astros -1.5 @ +152 via FanDuel Sportsbook
- Moneyline: Astros @ -140 via PointsBet (57% probability)
- Total: Over 8 @ -110 via Caesars Sportsbook (54% probability)
Our best bets are based on world-class modeling and gambling expertise to serve you the best possible plays every day of the year.
Even though the Mets are more likely to cover the run line, our best bet of Astros -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.
Mets vs. Astros Prediction
Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Mets vs. Houston, and click or tap on See Matchup to reveal more.
Dimers has full betting coverage of Wednesday's Mets-Astros matchup, including pregame predictions, computer picks, and live win probabilities.
Remember, DimersBOT updates often, so keep checking this page for the latest betting analysis ahead of Mets vs. Astros on Wednesday June 22, 2022.
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Mets vs. Astros 2022 Game Info
Wednesday's game between the Astros and Mets at Minute Maid Park is scheduled to commence at 2:10PM ET.
- Who: Houston Astros vs. New York Mets
- Date: Wednesday June 22, 2022
- Time: 2:10PM ET / 11:10AM PT
- Venue: Minute Maid Park
Want to join an online sportsbook and start betting on MLB? Check out the top sportsbook bonus offers in your state.
What MLB games are on today?
Now you've got the 411 on Mets vs. Astros, see the latest betting predictions for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.
Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!
Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.
