Mariners vs. Athletics Prediction and Odds - Sep 22, 2022

MLB action continues on Thursday at 3:37PM ET as the Seattle Mariners lock horns with the Oakland Athletics at Oakland Coliseum.

The Athletics will have Adrian Martinez (4-5, 5.77 ERA) start, pitting him against George Kirby (7-4, 2.98 ERA) for the Mariners.

Dimers' top betting picks for Mariners vs. Athletics, plus game predictions and best odds, are featured below.


Who will win Mariners vs. Athletics?

Based on advanced computer power and data, has simulated Thursday's Mariners-Athletics MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Mariners a 64% chance of winning against the Athletics.

More: Full Betting Guide for Mariners vs. Athletics

Mariners vs. Athletics Game Odds

  • Run Line: Athletics +1.5 (+122), Mariners -1.5 (-130)
  • Moneyline: Athletics +210, Mariners -245
  • Total: Over/Under 7 (-120/+100)

Run Line, Moneyline and Over/Under

The Athletics are currently +1.5 underdogs against the Mariners, with +122 at FanDuel Sportsbook the best odds currently available.

For the favored Mariners (-1.5) to cover the run line, BetMGM has the best odds currently on offer at -130.

FanDuel Sportsbook currently has the best moneyline odds for the Athletics at +210, which means you can throw down $100 to profit $210, earning a total payout of $310, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Mariners at -245, where you can risk $245 to win $100, for a total payout of $345, if they come out on top.

The Over/Under for total runs scored sits at 7 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Mariners and Athletics are a 50% chance of covering the run line, while the Over/Under total of 7 runs is a 58% chance of going Over.

More: Best Prop Bets Today

Best Bets for Mariners vs. Athletics


Every time you see a 🔥, that means it's one of Dimers' best free picks of the day across all major pro and college sports.

Dimers' best bets are based on world-class modeling and betting expertise to serve you the best possible plays 24/7/365.

While the Mariners are more likely to win the game, according to DimersBOT, taking the Athletics moneyline is the best option due to the 3.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at is pivotal to being profitable in the long run.

Mariners vs. Athletics Probabilities

Click or tap on See Matchup to reveal more.


Dimers has full betting coverage of Thursday's Mariners-Athletics matchup, including pregame predictions, free picks, and live scores.

Don't forget, DimersBOT updates frequently, so check this article for any changes to our betting insights before Mariners vs. Athletics on Thursday September 22, 2022.


Mariners vs. Athletics 2022 Game Info

Thursday's game between the Athletics and Mariners at Oakland Coliseum is scheduled to commence at 3:37PM ET.

  • Who: Seattle Mariners vs. Oakland Athletics
  • Date: Thursday September 22, 2022
  • Time: 3:37PM ET / 12:37PM PT
  • Venue: Oakland Coliseum

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What other MLB games are on today?

Now you've got the 411 on Mariners vs. Athletics, take a look at the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.

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