Guardians vs. Twins Prediction and Odds - Jun 23, 2022

Updated: Dec 21, 2023, 5:08 AM ET | First published: Jun 22, 2022, 4:57 AM ET

Guardians vs. Twins Prediction and Odds - Jun 23, 2022

The Minnesota Twins square off with the Cleveland Guardians in MLB action at Target Field on Thursday, beginning at 1:10PM ET.

Devin Smeltzer (3-1, 3.52 ERA) will be on the bump for the Twins, up against Zach Plesac (2-4, 4.41 ERA) for the Guardians.

Dimers' best betting picks for Guardians vs. Twins, as well as game predictions and betting odds, are featured in this article.

Who will win Guardians vs. Twins?

Using advanced machine learning and data, Dimers.com has simulated Thursday's Guardians-Twins MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Twins a 56% chance of winning against the Guardians.

More: Guardians vs. Twins Simulated 10K Times

Guardians vs. Twins Current Odds

Run Line: Twins -1.5 (+140), Guardians +1.5 (-154)
Moneyline: Twins -135, Guardians +122
Total: Over/Under 9.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Twins are -1.5 favorites against the Guardians, with +140 at Caesars Sportsbook the best odds currently available.

For the underdog Guardians (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -154.

DraftKings Sportsbook currently has the best moneyline odds for the Twins at -135, which means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Guardians at +122, where you can bet $100 to profit $122, earning a total payout of $222, if they win.

The Over/Under for total runs scored sits at 9.5 with BetMGM, which currently has the best odds for the Over at -115, while PointsBet currently has the best odds for the Under at +100.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 60% chance of covering the run line, while the 9.5-run Over/Under is a 54% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Guardians vs. Twins

Run Line: Guardians +1.5 @ -154 via FanDuel Sportsbook (60% probability)
Moneyline: Guardians @ +122 via FanDuel Sportsbook
Total: Over 9.5 @ -115 via BetMGM (54% probability)

Dimers' best bets are based on world-class modeling and wagering expertise to help you make more informed decisions with the legal sportsbooks in America.

While the Twins are more likely to win the game, according to DimersBOT, betting on the Guardians moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is one of the keys to achieving long-term profitability as a bettor.

Guardians vs. Twins Probabilities

Use our interactive widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. Minnesota, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Thursday's Guardians-Twins matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this page for the latest betting insights before Guardians vs. Twins on Thursday June 23, 2022.

Best Sportsbook Offer for Guardians vs. Twins

Are you looking to bet on Cleveland vs. Minnesota? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Thursday's Guardians-Twins game.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Guardians vs. Twins. If your bet doesn't win, FanDuel Sportsbook will give it back to you in site credit!

This offer is available to all new FanDuel Sportsbook users – no promo code needed!

Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee. Thank you for supporting the partners who make Dimers possible.

Guardians vs. Twins 2022 Game Info

Thursday's action between the Twins and Guardians at Target Field is scheduled to start at 1:10PM ET.

Who: Minnesota Twins vs. Cleveland Guardians
Date: Thursday June 23, 2022
Time: 1:10PM ET / 10:10AM PT
Venue: Target Field

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Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Guardians vs. Twins, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the best MLB betting previews available. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.

Written by

Dimers Data

Dimers Data delivers cold-blooded analysis straight from thousands of simulations run by predictive models built by our in-house team of data scientists and analysts. No hunches. No guesswork. Just pure, data-led insight serious bettors rely on to stay ahead.

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