Guardians vs. Tigers Prediction and Odds - May 27, 2022

The Detroit Tigers face the Cleveland Guardians in MLB action at Comerica Park on Friday, beginning at 7:10PM ET.

The Tigers will send Alex Faedo (1-1, 3.00 ERA) to the mound, pitting him against Shane Bieber (1-3, 3.55 ERA) for the Guardians.

Dimers' top betting picks for Guardians vs. Tigers, plus game predictions and best odds, are featured below.

Today's Cleveland vs. Detroit betting analysis is presented by PointsBet, which has an awesome 5x $100 Risk-Free Bets offer for new users.

Who will win Guardians vs. Tigers?

Using high-tech computer power and data, Dimers.com has simulated Friday's Guardians-Tigers MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Guardians a 60% chance of beating the Tigers.

More: Guardians vs. Tigers Simulated 10,000 Times

Guardians vs. Tigers Current Odds

• Run Line: Tigers +1.5 (-130), Guardians -1.5 (+120)
• Moneyline: Tigers +135, Guardians -149
• Total: Over/Under 7 (-120/+100)

Run Line, Moneyline and Over/Under

The Tigers are +1.5 underdogs against the Guardians, with -130 at DraftKings Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +120.

PointsBet currently has the best moneyline odds for the Tigers at +135, which means you can bet $100 to profit $135, earning a total payout of $235, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Guardians at -149, where you can risk $149 to win $100, for a total payout of $249, if they come out on top.

The Over/Under for total runs scored is set at 7 with Caesars Sportsbook, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Tigers (+1.5) are a 54% chance of covering the run line, while the 7-run Over/Under is a 61% chance of going Over.

More: Free Prop Picks

Best Bets for Guardians vs. Tigers

• Run Line: Guardians -1.5 @ +120 via FanDuel Sportsbook (1.0% edge)
• Moneyline: Guardians @ -149 via Caesars Sportsbook (60% probability)
• Total: Over 7 @ -120 via Caesars Sportsbook (61% probability) 🔥

If you see a 🔥, you know it's one of Dimers' best free picks of the day across any sport.

Dimers' best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays 24/7/365.

Although the Tigers are more likely to cover the run line, our best bet of Guardians -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Guardians vs. Tigers Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. Detroit, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Guardians-Tigers matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so check this page for any changes to our betting analysis ahead of Guardians vs. Tigers on Friday May 27, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Guardians vs. Tigers 2022 Game Info

Friday's action between the Tigers and Guardians at Comerica Park is scheduled to commence at 7:10PM ET.

• Who: Detroit Tigers vs. Cleveland Guardians
• Date: Friday May 27, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Comerica Park

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Want more MLB predictions like this?

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