Guardians vs. Royals Prediction and Odds - Sep 7, 2022

The Kansas City Royals and Cleveland Guardians meet in MLB at Kauffman Stadium on Wednesday, starting at 8:10PM ET.

Zack Greinke (4-8, 4.14 ERA) will be on the bump for the Royals, while the Guardians are going with Cody Morris (0-1, 9.00 ERA).

Dimers' best betting picks for Guardians vs. Royals, as well as game predictions and betting odds, are detailed below.

Who will win Guardians vs. Royals?

Based on advanced machine learning and data, Dimers.com has simulated Wednesday's Guardians-Royals MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Guardians a 56% chance of winning against the Royals.

More: Full Betting Guide for Guardians vs. Royals

Guardians vs. Royals Current Odds

• Run Line: Royals +1.5 (-140), Guardians -1.5 (+122)
• Moneyline: Royals +120, Guardians -140
• Total: Over/Under 8 (-104/-115)

Run Line, Moneyline and Over/Under

The Royals are listed as +1.5 underdogs versus the Guardians, with -140 at DraftKings Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +122.

DraftKings Sportsbook currently has the best moneyline odds for the Royals at +120, which means you can bet $100 to profit $120, earning a total payout of $220, if they win.

Meanwhile, BetMGM currently has the best moneyline odds for the Guardians at -140, where you can risk $140 to win $100, for a total payout of $240, if they come out on top.

The Over/Under for total runs scored sits at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -104, while Caesars Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 57% chance of covering the run line, while the Over/Under total of 8 runs is a 51% chance of going Over.

More: Best Prop Bets Today

Best Bets for Guardians vs. Royals

• Run Line: Royals +1.5 @ -140 via DraftKings Sportsbook (57% probability)
• Moneyline: Royals @ +120 via DraftKings Sportsbook
• Total: Over 8 @ -104 via FanDuel Sportsbook (51% probability)

Our best bets are based on world-class simulations and gambling intelligence to bring you the best possible plays 24/7/365.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the Royals moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers.com is one of the keys to achieving long-term profitability.

Guardians vs. Royals Prediction

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Dimers has full betting coverage of Wednesday's Guardians-Royals matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this page for the latest betting insights ahead of Guardians vs. Royals on Wednesday September 7, 2022.

Guardians vs. Royals 2022 Game Info

Wednesday's game between the Royals and Guardians at Kauffman Stadium is scheduled to begin at 8:10PM ET.

• Who: Cleveland Guardians vs. Kansas City Royals
• Date: Wednesday September 7, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Kauffman Stadium

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