Giants vs. Reds Prediction and Odds - May 28, 2022

The Cincinnati Reds face the San Francisco Giants in MLB action at Great American Ball Park on Saturday, beginning at 4:10PM ET.

Vladimir Gutierrez (0-6, 8.70 ERA) will start on the mound for the Reds, pitting him against Alex Wood (3-3, 4.82 ERA) for the Giants.

Dimers' free betting picks for Giants vs. Reds, as well as game predictions and best odds, are featured in this article.

This San Francisco vs. Cincinnati betting analysis is presented by PointsBet, which has a great 5x $100 Risk-Free Bets promo for new customers.

Who will win Giants vs. Reds?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Saturday's Giants-Reds MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Giants a 62% chance of getting the W against the Reds.

More: Full Betting Analysis for Giants vs. Reds

Giants vs. Reds Current Odds

• Run Line: Reds +1.5 (+105), Giants -1.5 (-111)
• Moneyline: Reds +160, Giants -179
• Total: Over/Under 10 (+100/-115)

Run Line, Moneyline and Over/Under

The Reds are +1.5 underdogs versus the Giants, with +105 at PointsBet the best odds currently available.

For the favored Giants (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -111.

DraftKings Sportsbook currently has the best moneyline odds for the Reds at +160, which means you can bet $100 to profit $160, earning a total payout of $260, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Giants at -179, where you can risk $179 to win $100, for a total payout of $279, if they come out on top.

The Over/Under is set at 10 with PointsBet, which currently has the best odds for the Over at +100, while DraftKings Sportsbook currently has the best odds for the Under at -115.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Giants and Reds are a 50% chance of covering the run line, while the 10-run Over/Under is a 55% chance of going Under.

More: Free Prop Picks

Best Bets for Giants vs. Reds

• Run Line: Reds +1.5 @ +105 via PointsBet (50% probability)
• Moneyline: Reds @ +160 via DraftKings Sportsbook
• Total: Under 10 @ -115 via DraftKings Sportsbook (55% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in the USA.

While the Giants are more likely to win the game, according to DimersBOT, taking the Reds moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers is crucial to achieving long-term profitability.

Giants vs. Reds Probabilities

Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. Cincinnati, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Giants-Reds matchup, including pregame predictions, top betting picks, and live scores.

Remember, DimersBOT updates often, so keep checking this page for any changes to our betting insights ahead of Giants vs. Reds on Saturday May 28, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Giants vs. Reds 2022 Game Info

Saturday's game between the Reds and Giants at Great American Ball Park is scheduled to begin at 4:10PM ET.

• Who: Cincinnati Reds vs. San Francisco Giants
• Date: Saturday May 28, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: Great American Ball Park

Looking to join an online sportsbook and start betting on MLB? Check out the best sports betting bonus offers in your state.

What other MLB games are on today?

The Giants and Reds aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for each and every MLB matchup in our MLB Bet Hub section.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.