D-Backs vs. Cubs Prediction and Odds - May 22, 2022

The Chicago Cubs take on the Arizona D-Backs in MLB action at Wrigley Field on Sunday, starting at 2:20PM ET.

The Cubs will have Wade Miley (1-0, 2.70 ERA) start, while the D-Backs will counter with Merrill Kelly (3-2, 3.27 ERA).

Dimers' free betting picks for D-Backs vs. Cubs, plus game predictions and best odds, are detailed in this article.

Today's Arizona vs. CHI Cubs betting analysis is presented by PointsBet, which has an outstanding 5x $100 Risk-Free Bets offer for new users.

Who will win D-Backs vs. Cubs?

Using cutting-edge computer power and data, Dimers.com has simulated Sunday's D-Backs-Cubs MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Cubs a 52% chance of defeating the D-Backs .

More: Full Betting Guide for D-Backs vs. Cubs

D-Backs vs. Cubs Current Odds

• Run Line: Cubs -1.5 (+170), D-Backs +1.5 (-190)
• Moneyline: Cubs -125, D-Backs +112
• Total: Over/Under 7.5 (+105/-115)

Run Line, Moneyline and Over/Under

The Cubs are -1.5 favorites versus the D-Backs, with +170 at PointsBet the best odds currently available.

For the underdog D-Backs (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -190.

Caesars Sportsbook currently has the best moneyline odds for the Cubs at -125. That means you can risk $125 to win $100, for a total payout of $225, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the D-Backs at +112, where you can bet $100 to profit $112, earning a total payout of $212, if they win.

The Over/Under sits at 7.5 with PointsBet, which currently has the best odds for the Over at +105, while BetMGM currently has the best odds for the Under at -115.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the D-Backs (+1.5) are a 66% chance of covering the run line, while the Over/Under total of 7.5 runs is considered an equal 50-50 chance of hitting.

More: Free Prop Picks

Best Bets for D-Backs vs. Cubs

• Run Line: D-Backs +1.5 @ -190 via BetMGM (66% probability)
• Moneyline: D-Backs @ +112 via FanDuel Sportsbook (0.8% edge)
• Total: Over 7.5 @ +105 via PointsBet (50% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays 24/7/365.

While the Cubs are more likely to win the game, according to DimersBOT, taking the D-Backs moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers is one of the keys to being a profitable bettor in the long run.

D-Backs vs. Cubs Probabilities

Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Arizona vs. CHI Cubs, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Sunday's D-Backs-Cubs matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates frequently, so check this article for the latest betting analysis ahead of D-Backs vs. Cubs on Sunday May 22, 2022.

Get a Risk-Free Bet for D-Backs vs. Cubs

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

D-Backs vs. Cubs 2022 Game Info

Sunday's action between the Cubs and D-Backs at Wrigley Field is scheduled to commence at 2:20PM ET.

• Date: Sunday May 22, 2022
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

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Want more MLB analysis like this?

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That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets. This allows us to create the most authoritative MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not take a look around?

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.