Cubs vs. Orioles Prediction and Odds - Jun 8, 2022

The Baltimore Orioles and Chicago Cubs meet in MLB at Oriole Park at Camden Yards on Wednesday, starting at 7:05PM ET.

Jordan Lyles (3-4, 4.50 ERA) will be on the bump for the Orioles, pitting him against Marcus Stroman (2-5, 5.32 ERA) for the Cubs.

Dimers' top betting picks for Cubs vs. Orioles, plus game predictions and best odds, are detailed in this article.

Who will win Cubs vs. Orioles?

Based on cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Cubs-Orioles MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Cubs a 52% chance of defeating the Orioles.

More: Free Betting Analysis for Cubs vs. Orioles

Cubs vs. Orioles Current Odds

• Run Line: Orioles +1.5 (-150), Cubs -1.5 (+140)
• Moneyline: Orioles +110, Cubs -125
• Total: Over/Under 9 (+110/-120)

Run Line, Moneyline and Over/Under

The Orioles are +1.5 underdogs versus the Cubs, with -150 at BetMGM the best odds currently available.

For the favored Cubs (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at +140.

BetMGM currently has the best moneyline odds for the Orioles at +110. That means you can bet $100 to profit $110, earning a total payout of $210, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Cubs at -125, where you can risk $125 to win $100, for a total payout of $225, if they come out on top.

The Over/Under for total runs scored is set at 9 with PointsBet, which currently has the best odds for the Over at +110, while Caesars Sportsbook currently has the best odds for the Under at -120.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 60% chance of covering the run line, while the 9-run Over/Under is a 53% chance of going Under.

More: Free Prop Picks

Best Bets for Cubs vs. Orioles

• Run Line: Orioles +1.5 @ -150 via BetMGM (60% probability)
• Moneyline: Orioles @ +110 via BetMGM (0.1% edge)
• Total: Over 9 @ +110 via PointsBet

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays 24/7.

While the Cubs are more likely to win the game, according to DimersBOT, betting on the Orioles moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to achieving long-term profitability as a sports bettor.

Furthermore, despite the Under being more likely to hit on this occasion, Over 9 is our best bet on account of the better odds (+110) that are available from PointsBet.

Cubs vs. Orioles Prediction

Use our interactive widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. Baltimore, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Cubs-Orioles matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep checking this article for the latest betting insights before Cubs vs. Orioles on Wednesday June 8, 2022.

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Cubs vs. Orioles 2022 Game Info

Wednesday's action between the Orioles and Cubs at Oriole Park at Camden Yards is scheduled to start at 7:05PM ET.

• Who: Baltimore Orioles vs. Chicago Cubs
• Date: Wednesday June 8, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Oriole Park at Camden Yards

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What other MLB games are on today?

Now you've got the 411 on Cubs vs. Orioles, check out the latest betting predictions for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, plus our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.