Cardinals vs. Cubs Prediction and Odds - Jun 3, 2022

The Chicago Cubs face the St Louis Cardinals in MLB action at Wrigley Field on Friday, commencing at 2:20PM ET.

The Cubs will have Marcus Stroman (2-4, 3.95 ERA) start, while the Cardinals are going with Miles Mikolas (3-3, 2.67 ERA).

Dimers' best betting picks for Cardinals vs. Cubs, plus game predictions and best odds, are detailed in this article.

Who will win Cardinals vs. Cubs?

Based on advanced computer power and data, Dimers.com has simulated Friday's Cardinals-Cubs MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Cardinals a 52% chance of beating the Cubs.

More: Cardinals vs. Cubs Simulated 10,000 Times

Cardinals vs. Cubs Odds

• Run Line: Cubs +1.5 (-179), Cardinals -1.5 (+158)
• Moneyline: Cubs -108, Cardinals -108
• Total: Over/Under 8.5 (-105/-110)

Run Line, Moneyline and Over/Under

The Cubs are +1.5 underdogs versus the Cardinals, with -179 at Caesars Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +158.

In a sign of how close this game is expected to be, both the Cubs and Cardinals are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Cubs at -108. That means you can risk $108 to win $100, for a total payout of $208, if they get the W.

Meanwhile, FanDuel Sportsbook also has the best moneyline odds for the Cardinals at -108, where you can risk $108 to win $100, for a total payout of $208, if they come out on top.

The Over/Under for total runs scored sits at 8.5 with PointsBet, which currently has the best odds for the Over at -105, while FanDuel Sportsbook currently has the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 8.5 runs is considered an equal 50-50 chance of hitting.

More: Best Prop Bets to Make Today

Best Bets for Cardinals vs. Cubs

• Run Line: Cardinals -1.5 @ +158 via FanDuel Sportsbook (0.1% edge)
• Moneyline: Cardinals @ -108 via FanDuel Sportsbook (52% probability)
• Total: Over 8.5 @ -105 via PointsBet (50% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays every day of the year.

Although the Cubs are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Cardinals vs. Cubs Betting Guide

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. CHI Cubs, and click or tap on See Matchup for more.

Dimers has full betting coverage of Friday's Cardinals-Cubs matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this page for any changes to our betting insights before Cardinals vs. Cubs on Friday June 3, 2022.

Bet $5 on Cardinals-Cubs, Win $200 Guaranteed

FanDuel Sportsbook is giving new players $200 in Free Bets, win or lose, when you place your first $5 bet on Cardinals vs. Cubs.

Simply join FanDuel Sportsbook using this exclusive link, make a first-time deposit, and place (as your first real-money wager) a $5 bet on Cardinals vs. Cubs to get $200 in Free Bets added to your account – guaranteed.

Don't miss this chance to score on America's No. 1 Sportsbook.

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cardinals vs. Cubs 2022 Game Info

Friday's matchup between the Cubs and Cardinals at Wrigley Field is scheduled to commence at 2:20PM ET.

• Who: Chicago Cubs vs. St Louis Cardinals
• Date: Friday June 3, 2022
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

Looking to join an online sportsbook and start betting on MLB? We've listed the best available welcome offers for each and every legal betting state.

What other MLB games are on today?

Now you've got the 411 on Cardinals vs. Cubs, see the latest betting analysis for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.