Brewers vs. Padres Prediction and Odds - May 25, 2022

The San Diego Padres square off with the Milwaukee Brewers in MLB action at PETCO Park on Wednesday, starting at 4:10PM ET.

The Padres will have Yu Darvish (4-1, 3.91 ERA) start, up against Aaron Ashby (0-3, 3.49 ERA) for the Brewers.

Dimers' free betting picks for Brewers vs. Padres, as well as game predictions and best odds, are detailed in this article.

Today's Milwaukee vs. San Diego betting preview is proudly sponsored by PointsBet, which has a 5x $100 Risk-Free Bets offer for new customers.

Who will win Brewers vs. Padres?

Based on state-of-the-art computer power and data, Dimers.com has simulated Wednesday's Brewers-Padres MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Padres a 54% chance of beating the Brewers.

More: Brewers vs. Padres Simulated 10K Times

Brewers vs. Padres Odds

• Run Line: Padres -1.5 (+158), Brewers +1.5 (-179)
• Moneyline: Padres -140, Brewers +125
• Total: Over/Under 7.5 (+100/-115)

Run Line, Moneyline and Over/Under

The Padres are -1.5 favorites against the Brewers, with +158 at FanDuel Sportsbook the best odds currently available.

For the underdog Brewers (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -179.

PointsBet currently has the best moneyline odds for the Padres at -140. That means you can risk $140 to win $100, for a total payout of $240, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Brewers at +125, where you can put down $100 to profit $125, earning a total payout of $225, if they win.

The Over/Under sits at 7.5 with BetMGM, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Brewers (+1.5) are a 65% chance of covering the run line, while the Over/Under total of 7.5 runs is a 54% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets for Brewers vs. Padres

• Run Line: Brewers +1.5 @ -179 via Caesars Sportsbook (65% probability)
• Moneyline: Brewers @ +125 via Caesars Sportsbook (1.4% edge)
• Total: Under 7.5 @ -115 via FanDuel Sportsbook (54% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in your state.

While the Padres are more likely to win the game, according to DimersBOT, betting on the Brewers moneyline is the best option due to the 1.4% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published on Dimers is one of the keys to achieving long-term profitability as a bettor.

Brewers vs. Padres Probabilities

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Milwaukee vs. San Diego, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Brewers-Padres matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this page for any changes to our betting insights before Brewers vs. Padres on Wednesday May 25, 2022.

Best Sportsbook Offer for Brewers vs. Padres

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Brewers vs. Padres 2022 Game Info

Wednesday's action between the Padres and Brewers at PETCO Park is scheduled to start at 4:10PM ET.

• Who: San Diego Padres vs. Milwaukee Brewers
• Date: Wednesday May 25, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: PETCO Park

Ready to join an online sportsbook and start betting on MLB today? We've reviewed the best available sign-up offers for each legal betting state.

What MLB games are on today?

Now you've got the 411 on Brewers vs. Padres, see the latest betting analysis for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.