Athletics vs. Astros Prediction and Odds - Sep 16, 2022

The Houston Astros and Oakland Athletics lock horns in MLB at Minute Maid Park on Friday, starting at 8:10PM ET.

Justin Verlander (16-3, 1.84 ERA) will start for the Astros, up against Adrian Martinez (4-4, 5.59 ERA) for the Athletics.

Dimers' top betting picks for Athletics vs. Astros, plus game predictions and betting odds, are featured below.

Who will win Athletics vs. Astros?

Using state-of-the-art machine learning and data, Dimers.com has simulated Friday's Athletics-Astros MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Astros a 75% chance of getting the W against the Athletics.

More: Free Betting Guide for Athletics vs. Astros

Athletics vs. Astros Odds

• Run Line: Astros -1.5 (-150), Athletics +1.5 (+135)
• Moneyline: Astros -350, Athletics +300
• Total: Over/Under 7.5 (+104/-115)

Run Line, Moneyline and Over/Under

The Astros are currently -1.5 favorites versus the Athletics, with -150 at DraftKings Sportsbook the best odds currently available.

For the underdog Athletics (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at +135.

BetMGM currently has the best moneyline odds for the Astros at -350. That means you can risk $350 to win $100, for a total payout of $450, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Athletics at +300, where you can bet $100 to profit $300, earning a total payout of $400, if they win.

The Over/Under for total runs scored is set at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at +104, while Caesars Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Astros (-1.5) are a 56% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Best Prop Bets Today

Best Bets for Athletics vs. Astros

• Run Line: Athletics +1.5 @ +135 via Caesars Sportsbook (1.3% edge)
• Moneyline: Athletics @ +300 via FanDuel Sportsbook (0.4% edge)
• Total: Over 7.5 @ +104 via FanDuel Sportsbook (52% probability)

Our best bets are based on detailed simulations and betting expertise to help you make better decisions with the legal sportsbooks in the United States.

Although the Astros are more likely to cover the run line, our best bet of Athletics +1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

And while the Astros are more likely to win the game, according to DimersBOT, taking the Athletics moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is crucial to being profitable in the long run.

Athletics vs. Astros Prediction

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Dimers has full coverage of Friday's Athletics-Astros matchup, including pregame predictions, computer picks, and live scores.

Remember, DimersBOT updates frequently, so refresh this article for the latest betting analysis before Athletics vs. Astros on Friday September 16, 2022.

Athletics vs. Astros 2022 Game Info

Friday's matchup between the Astros and Athletics at Minute Maid Park is scheduled to commence at 8:10PM ET.

• Who: Oakland Athletics vs. Houston Astros
• Date: Friday September 16, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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What other MLB games are on today?

Now you've got the 411 on Athletics vs. Astros, take a look at the latest betting analysis for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.