Astros vs. Mariners Prediction and Odds - May 27, 2022

The Seattle Mariners and Houston Astros lock horns in MLB at T-Mobile Park on Friday, starting at 9:40PM ET.

Chris Flexen (1-6, 4.98 ERA) will start on the mound for the Mariners, up against Justin Verlander (6-1, 1.22 ERA) for the Astros.

Dimers' free betting picks for Astros vs. Mariners, plus game predictions and best odds, are detailed below.

Today's Houston vs. Seattle betting analysis is sponsored by PointsBet, which has an outstanding 5x $100 Risk-Free Bets promo for new users.

Who will win Astros vs. Mariners?

Based on trusted computer power and data, Dimers.com has simulated Friday's Astros-Mariners MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Astros a 63% chance of beating the Mariners.

More: Astros vs. Mariners Simulated 10,000 Times

Astros vs. Mariners Current Odds

• Run Line: Mariners +1.5 (+110), Astros -1.5 (-114)
• Moneyline: Mariners +180, Astros -200
• Total: Over/Under 7.5 (+100/-120)

Run Line, Moneyline and Over/Under

The Mariners are +1.5 underdogs against the Astros, with +110 at PointsBet the best odds currently available.

For the favored Astros (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at -114.

BetMGM currently has the best moneyline odds for the Mariners at +180. That means you can bet $100 to profit $180, earning a total payout of $280, if they win.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Astros at -200, where you can risk $200 to win $100, for a total payout of $300, if they come out on top.

The Over/Under for total runs scored is set at 7.5 with BetMGM, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Astros and Mariners are a 50% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Astros vs. Mariners

• Run Line: Mariners +1.5 @ +110 via PointsBet (50% probability)
• Moneyline: Mariners @ +180 via BetMGM (0.9% edge)
• Total: Over 7.5 @ +100 via BetMGM (52% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to help you make more informed investments with the legal sportsbooks in America.

While the Astros are more likely to win the game, according to DimersBOT, betting on the Mariners moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers is crucial to being profitable in the long run.

Astros vs. Mariners Probabilities

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Seattle, and click or tap on See Matchup for more.

Dimers has full coverage of Friday's Astros-Mariners matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this article for any changes to our betting analysis before Astros vs. Mariners on Friday May 27, 2022.

Risk-Free Bet for Astros vs. Mariners

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Mariners 2022 Game Info

Friday's matchup between the Mariners and Astros at T-Mobile Park is scheduled to commence at 9:40PM ET.

• Who: Seattle Mariners vs. Houston Astros
• Date: Friday May 27, 2022
• Time: 9:40PM ET / 6:40PM PT
• Venue: T-Mobile Park

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What MLB games are on today?

Now you've got the 411 on Astros vs. Mariners, get the latest betting predictions for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.