Yankees vs. White Sox Prediction and Odds - May 15, 2022

The Chicago White Sox and New York Yankees meet in MLB at Guaranteed Rate Field on Sunday, starting at 2:10PM ET.

Michael Kopech (0-0, 0.93 ERA) will start on the mound for the White Sox, pitting him against Nestor Cortes Jr. (1-1, 1.41 ERA) for the Yankees.

Dimers' best betting picks for Yankees vs. White Sox, as well as game predictions and best odds, are featured in this article.

Today's NY Yankees vs. CHI White Sox betting preview is proudly sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Yankees vs. White Sox?

Using cutting-edge computer power and data, Dimers.com has simulated Sunday's Yankees-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently can't split the two teams, giving both the Yankees and White Sox a 50% chance of winning the game.

More: Free Betting Analysis for Yankees vs. White Sox

Yankees vs. White Sox Current Odds

• Run Line: White Sox +1.5 (-149), Yankees -1.5 (+140)
• Moneyline: White Sox +110, Yankees -125
• Total: Over/Under 7.5 (+100/-110)

Run Line, Moneyline and Over/Under

The White Sox are +1.5 underdogs versus the Yankees, with -149 at Caesars Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +140.

BetMGM currently has the best moneyline odds for the White Sox at +110. That means you can bet $100 to profit $110, earning a total payout of $210, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Yankees at -125, where you can risk $125 to win $100, for a total payout of $225, if they come out on top.

The Over/Under is set at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while PointsBet currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) are a 62% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Yankees vs. White Sox

• Run Line: White Sox +1.5 @ -149 via Caesars Sportsbook (62% probability)
• Moneyline: White Sox @ +110 via BetMGM (50% probability)
• Total: Over 7.5 @ +100 via DraftKings Sportsbook (54% probability) 🔥

Any time you see a 🔥, you know it's one of Dimers' best free picks of the day across all sports.

Dimers' best bets are based on detailed simulations and betting intelligence to help you make smarter decisions with the legal sportsbooks in the United States.

Yankees vs. White Sox Betting Guide

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. CHI White Sox, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Sunday's Yankees-White Sox matchup, including pregame predictions, computer picks, and live scores.

Remember, DimersBOT updates frequently, so keep checking this article for the latest betting insights ahead of Yankees vs. White Sox on Sunday May 15, 2022.

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Yankees vs. White Sox 2022 Game Info

Sunday's action between the White Sox and Yankees at Guaranteed Rate Field will start at 2:10PM ET.

• Date: Sunday May 15, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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Want more MLB previews like this?

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We use the power of predictive analytics to find edges in the markets so we can publish the best MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.