Yankees vs. Orioles Prediction and Odds - Apr 16, 2022

The Baltimore Orioles face the New York Yankees in MLB action at Oriole Park at Camden Yards on Saturday, commencing at 7:05PM EDT.

Tyler Wells (0-1, 21.60 ERA) will start for the Orioles, up against Jameson Taillon (0-1, 3.60 ERA) for the Yankees.

Dimers' top betting picks for Yankees vs. Orioles, as well as game predictions and best odds, are detailed in this article.

Who will win Yankees vs. Orioles?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Saturday's Yankees-Orioles MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Yankees a 60% chance of beating the Orioles.

More: Free Betting Analysis for Yankees vs. Orioles

Yankees vs. Orioles Odds

• Run Line: Orioles +1.5, Yankees -1.5
• Moneyline: Orioles +155, Yankees -175
• Total: Over/Under 8.5

Run Line, Moneyline and Over/Under

The Orioles are +1.5 underdogs versus the Yankees, with +105 at DraftKings Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Orioles at +155. That means you can bet $100 to profit $155, earning a total payout of $255, if they win.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Yankees at -175, where you can risk $175 to win $100, for a total payout of $275, if they come out on top.

The Over/Under for total runs scored is set at 8.5 with PointsBet, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, make sure you check all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 51% chance of covering the run line, while the Over/Under total of 8.5 runs is a 55% chance of going Over.

More: Predictions for Every MLB Game

Best Bets for Yankees vs. Orioles

• Run Line: Orioles +1.5 @ +105 via DraftKings Sportsbook (51% probability)
• Moneyline: Orioles @ +155 via BetMGM (1.5% edge)
• Total: Over 8.5 @ -115 via PointsBet (55% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every time.

While the Yankees are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option due to the 1.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is crucial to achieving long-term profitability.

Yankees vs. Orioles Betting Guide

Use our widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. Baltimore, and click or tap on See Matchup for more.

Dimers has full coverage of Saturday's Yankees-Orioles matchup, including pre-game predictions, free picks, and live win probabilities.

Remember, DimersBOT updates frequently, so check this page for the latest betting insights ahead of Yankees vs. Orioles on Saturday April 16, 2022.

Get a Risk-Free Bet for Yankees vs. Orioles

Are you looking to bet on NY Yankees vs. Baltimore? Join FanDuel Sportsbook today and get a risk-free first bet up to $1,000, which you can use on Saturday's Yankees-Orioles matchup.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Yankees vs. Orioles. If your bet doesn't win, FanDuel Sportsbook will give it back to you in site credit!

This offer is available to all new FanDuel Sportsbook users – no promo code required!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Yankees vs. Orioles 2022 Game Info

When do the Orioles play the Yankees?

• Date: Saturday April 16, 2022
• Time: 7:05PM EDT / 4:05PM PDT
• Venue: Oriole Park at Camden Yards

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What other MLB games are on today?

The Yankees and Orioles aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB matchup via our MLB Predictions section.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.