Yankees vs. Orioles Prediction and Odds - Apr 15, 2022

The Baltimore Orioles and New York Yankees lock horns in the MLB at Oriole Park at Camden Yards on Friday, starting at 7:05PM EDT.

Jordan Lyles (0-1, 9.00 ERA) will start on the mound for the Orioles, pitting him against Jordan Montgomery (0-0, 8.10 ERA) for the Yankees.

Dimers' free betting picks for Yankees vs. Orioles, as well as game predictions and best odds, are featured in this article.

Who will win Yankees vs. Orioles?

Based on trusted machine learning and data, Dimers.com has simulated Friday's Yankees-Orioles MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Yankees a 63% chance of beating the Orioles.

More: Free Betting Analysis for Yankees vs. Orioles

Yankees vs. Orioles Game Odds

• Run Line: Orioles +1.5, Yankees -1.5
• Moneyline: Orioles +180, Yankees -200
• Total: Over/Under 9.5

Run Line, Moneyline and Over/Under

The Orioles are currently +1.5 underdogs against the Yankees, with +110 at DraftKings Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at -126.

Caesars Sportsbook currently has the best moneyline odds for the Orioles at +180. That means you can bet $100 to profit $180, earning a total payout of $280, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the Yankees at -200, where you can risk $200 to win $100, for a total payout of $300, if they come out on top.

The Over/Under is set at 9.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +110, as well as the best odds for the Under at -130.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Yankees (-1.5) are a 52% chance of covering the run line, while the 9.5-run Over/Under is a 51% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Yankees vs. Orioles

• Run Line: Orioles +1.5 @ +110 via DraftKings Sportsbook (0.7% edge)
• Moneyline: Orioles @ +180 via Caesars Sportsbook (1.3% edge)
• Total: Over 9.5 @ +110 via DraftKings Sportsbook (51% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make smarter investments with the legal sportsbooks in the USA.

Although the Yankees are more likely to cover the run line, our best bet of Orioles +1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

And while the Yankees are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option because of the 1.3% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers.com is crucial to being a profitable bettor in the long run.

Yankees vs. Orioles Probabilities

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. Baltimore, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's Yankees-Orioles matchup, including pre-game predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting insights before Yankees vs. Orioles on Friday April 15, 2022.

Best Betting Promo for Yankees vs. Orioles

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Yankees vs. Orioles 2022 Game Info

When do the Orioles play the Yankees?

• Date: Friday April 15, 2022
• Time: 7:05PM EDT / 4:05PM PDT
• Venue: Oriole Park at Camden Yards

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Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Yankees vs. Orioles, all you've gotta do is visit our MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the best MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.