Yankees vs. Blue Jays Prediction and Odds - May 4, 2022

The Toronto Blue Jays take on the New York Yankees in MLB action at Rogers Centre on Wednesday, beginning at 7:07PM ET.

Yusei Kikuchi (0-1, 5.52 ERA) will be on the bump for the Blue Jays, while the Yankees will counter with Nestor Cortes Jr. (1-0, 1.31 ERA).

Dimers' top betting picks for Yankees vs. Blue Jays, as well as game predictions and best odds, are detailed in this article.

This NY Yankees vs. Toronto betting analysis is presented by PointsBet, which has a tasty 5x $100 Risk-Free Bets offer for new users.

Who will win Yankees vs. Blue Jays?

Using trusted machine learning and data, Dimers.com has simulated Wednesday's Yankees-Blue Jays MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Yankees a 55% chance of winning against the Blue Jays.

More: Free Betting Analysis for Yankees vs. Blue Jays

Yankees vs. Blue Jays Game Odds

• Run Line: Blue Jays +1.5 (-130), Yankees -1.5 (+112)
• Moneyline: Blue Jays +140, Yankees -155
• Total: Over/Under 8 (-120/+105)

Run Line, Moneyline and Over/Under

The Blue Jays are +1.5 underdogs against the Yankees, with -130 at Caesars Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +112.

Caesars Sportsbook currently has the best moneyline odds for the Blue Jays at +140. That means you can throw down $100 to profit $140, earning a total payout of $240, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the Yankees at -155, where you can risk $155 to win $100, for a total payout of $255, if they come out on top.

The Over/Under for total runs scored sits at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at -120, while PointsBet currently has the best odds for the Under at +105.

As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Blue Jays (+1.5) are a 59% chance of covering the run line, while the 8-run Over/Under is a 57% chance of going Over.

More: Best Bets for Every MLB Game

Best Bets for Yankees vs. Blue Jays

• Run Line: Blue Jays +1.5 @ -130 via Caesars Sportsbook (59% probability)
• Moneyline: Blue Jays @ +140 via Caesars Sportsbook (3.7% edge)
• Total: Over 8 @ -120 via DraftKings Sportsbook (57% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays 24/7/365.

While the Yankees are more likely to win the game, according to DimersBOT, taking the Blue Jays moneyline is the best option due to the 3.7% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is pivotal to being profitable in the long run.

Yankees vs. Blue Jays Betting Guide

Use our widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. Toronto, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Yankees-Blue Jays matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this article for the latest betting insights before Yankees vs. Blue Jays on Wednesday May 4, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Yankees vs. Blue Jays 2022 Game Info

When do the Blue Jays play the Yankees?

• Date: Wednesday May 4, 2022
• Time: 7:07PM ET / 4:07PM PT
• Venue: Rogers Centre

Ready to join an online sportsbook and start betting on MLB? We've listed the best available sign-up offers for each legal betting state.

What MLB games are on today?

The Yankees and Blue Jays aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every MLB game via our MLB Predictions section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.