Wyoming vs. South Dakota State prediction: Wyoming favored to win men's college basketball matchup [12/15/2025]

South Dakota State and Wyoming will lock horns in men's college basketball action at Sanford Pentagon on Monday, starting at 8:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects Wyoming as the most likely winner of the Wyoming vs. South Dakota State game.

This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Wyoming vs. South Dakota State prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Monday's NCAA basketball game between Wyoming and South Dakota State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Wyoming a 65% chance of beating South Dakota State. Our predicted final score has Wyoming winning 77-73.

According to our model, South Dakota State (+5.5) has a 58% chance of covering the spread, while the over/under total of 150.5 points has a 51% chance of staying under.

Wyoming vs. South Dakota State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Wyoming vs. South Dakota State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: