Wisconsin vs. Nebraska prediction: Nebraska favored to win men's college basketball matchup [12/10/2025]

Men's college basketball action continues on Wednesday at 9:00PM ET as Wisconsin squares off with Nebraska in men's college basketball action at Pinnacle Bank Arena.

Based on the latest simulations, Dimers' proven college basketball model predicts Nebraska as the most likely winner of the Wisconsin vs. Nebraska game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Wisconsin vs. Nebraska prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Wisconsin and Nebraska 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Nebraska a 55% chance of defeating Wisconsin. Our predicted final score has Nebraska winning 80-78.

According to our model, Wisconsin (+1.5) has a 53% chance of covering the spread, while the 157.5-point over/under has an equal 50-50 chance of hitting.

Wisconsin vs. Nebraska odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Wisconsin vs. Nebraska picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: